Active Recombinant Human BIRC7, His-tagged

• Cat.No.: BIRC7-432H
• Product Overview: Recombinant Human BIRC7 (Accession # AF311388) Met1-Ser280, fused with a C-terminal 6-His tag, was produced in E. coli-derived.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Predicted N Terminal: Met1
• Form: Supplied as a 0.2 µm filtered solution in HEPES, NaCl and DTT.
• Bio-activity: Measured by its ability to reverse the inhibition of DEVD-AFC cleavage activity in cell extracts activated by addition of cytochrome c and dATP. The IC50 for this effect is typically 1.0-2.0 µM. Optimal dilutions should be determined by each laboratory for each application.
• Molecular Mass: Recombinant Human BIRC7, His-tagged has a calculated MW of 32 kDa. In SDS-PAGE migrates as 36 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: BIRC7 baculoviral IAP repeat containing 7 [ Homo sapiens ]
• Official Symbol: BIRC7
• Synonyms: BIRC7; baculoviral IAP repeat containing 7; baculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; livin; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; ML IAP; mliap; RNF50; RING finger protein 50; LIVIN; MLIAP; ML-IAP
• Gene ID: 79444
• mRNA Refseq: NM_022161
• Protein Refseq: NP_071444
• MIM: 605737
• UniProt ID: Q96CA5
• Chromosome Location: 20q13.3