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Recombinant Mouse Mpl, Fc Chimera

Cat.No.: Mpl-496M
Product Overview: Recombinant Mouse Mpl (Accession # CAA52031) was produced in Mouse myeloma cell line, NS0-derived.
Source: NSO cells
Species: Mouse
Tag: Fc Chimera
Predicted N Terminal: Met
Form: Lyophilized from a 0.2 µm filtered solution in PBS and EDTA.
Bio-activity: Measured by its ability to inhibit the Tpo-dependent proliferation of MO7e human megakaryocytic leukemic cells.The ED50 for this effect is typically 0.1-0.4 µg/mL in the presence of 4 ng/mL of Recombinant Mouse Thrombopoietin/Tpo.
Molecular Mass: Recombinant Mouse Mpl, Fc Chimera has a calculated MW of 79.6 kDa (monomer). In SDS-PAGE migrates as 95-110 kDa, reducing conditions.
Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name: Mpl myeloproliferative leukemia virus oncogene [ Mus musculus ]
Official Symbol: Mpl
Synonyms: MPL; myeloproliferative leukemia virus oncogene; thrombopoietin receptor; proto-oncogene c-Mpl; myeloproliferative leukemia protein; CD110; TPO-R; c-mpl; hlb219; c-mpl-I; c-mpl-II;
Gene ID: 17480
mRNA Refseq: NM_001122949
Protein Refseq: NP_001116421
MIM:

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