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Active Recombinant Human GDF9

Cat.No. : GDF9-999H
Product Overview : Recombinant Human GDF9 (Accession # O60383) Gly320-Arg454, fused with , was produced in Human embryonic kidney cell, HEK293-derived.
  • Specification
  • Gene Information
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Source : HEK293 Cells
Species : Human
Predicted N Terminal : Gly320
Form : Lyophilized from a 0.2 µm filtered solution in HCl with BSA as a carrier protein.
Bio-activity : Measured by its ability to induce Smad2 phosphorylation in P19 mouse embryonal carcinoma cells. Mazerbourg, S. et al. (2004) Mol. Endocrinol. 18:653.50-100 ng/mL of Recombinant Human GDF-9 can effectively induce Smad2 phosphorylation.
Molecular Mass : Recombinant Human GDF9 has a calculated MW of 16 kDa (monomer). In SDS-PAGE migrates as 20-22 kDa, reducing conditions.
Protein length : Gly320-Arg454
Purity : >95%, by SDS-PAGE with silver staining.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : GDF9 growth differentiation factor 9 [ Homo sapiens ]
Official Symbol : GDF9
Synonyms : GDF9; growth differentiation factor 9; growth/differentiation factor 9; GDF-9;
Gene ID : 2661
mRNA Refseq : NM_005260
Protein Refseq : NP_005251
MIM : 601918
UniProt ID : O60383
Chromosome Location : 5q31.1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does GDF9 influence the proliferation and differentiation of granulosa cells in the ovary? 03/26/2021

GDF9 stimulates granulosa cell proliferation and differentiation, essential for healthy ovarian function.

What are the mechanisms by which GDF9 modulates intra-ovarian signaling pathways? 10/12/2020

GDF9 interacts with intra-ovarian signaling pathways, coordinating follicle development and ovulation.

How do alterations in GDF9 expression or function affect embryonic development and early pregnancy? 09/17/2020

Changes in GDF9 expression impact embryonic development and the success of early pregnancy stages.

What role does GDF9 play in fertility and reproductive outcomes in females? 11/28/2019

GDF9 significantly impacts female fertility, affecting egg quality and reproductive potential.

What is the impact of GDF9 mutations on the pathogenesis of ovarian dysfunctions and disorders? 04/28/2019

Mutations in GDF9 can lead to ovarian disorders, impacting follicle development and female fertility.

How does GDF9 regulate ovarian follicle development and oocyte maturation? 04/22/2019

GDF9 is crucial for ovarian follicle growth and oocyte maturation, influencing female fertility.

How does GDF9 contribute to the regulation of steroidogenesis in ovarian cells? 09/30/2018

GDF9 regulates steroid hormone production in ovarian cells, influencing reproductive hormone balance.

Customer Reviews (3)

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Reviews
11/14/2021

    Expertise in peptide synthesis, accelerates our peptide-related projects.

    08/24/2020

      Swift protein quantification, improves data reliability in our experiments.

      01/31/2019

        Outstanding protein-protein interaction studies, boost our research efforts.

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