"VAMP2" Related Products

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Recombinant Human VAMP2

Cat. No. : VAMP2-216H
Product Overview : Recombinant Human VAMP2 produced inE.Coliis a single, non-glycosylated polypeptide chain. The protein contains 126 amino acids and has a molecular mass of 13.8 kDa.
Description : Synaptobrevin 2 which is an 18 kDa integral membrane protein localized to the cytoplasmic surface of synaptic vesicle, consists of a proline-rich N-terminal region, a highly conserved hydrophilic domain, followed by a transmembrane anchor and a C-terminal. Synaptobrevin 2 is predominantly expressed in Langerhans islets and glomerular cells. The N-terminal domain of the protein (residues 1-89) forms a specific SNARE complex with the target membrane-associated t- or Q-SNAREs syntaxin 1 and SNAP-25.
Source : Escherichia Coli.
Amino Acid Sequence : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSA TAATAPPAAP AGEGGPPAPP PNLTSNRRLQ QTQAQVDEVV DIMRVNVDKV LERDQKLSEL DDRADALQAG ASQFETSAAKLKRKYW
Physical Appearance : Sterile Filtered colorless solution.
Purity : Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation : The protein solution (1mg/ml) contains 1X PBS and 1mM EDTA.
Stability : Synaptobrevin although stable 14°Cfor 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Gene Name : VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) [ Homo sapiens ]
Synonyms :
VAMP2; vesicle-associated membrane protein 2 (synaptobrevin 2); SYB2; VAMP-2; FLJ11460; VAMP2; HGNC:12643; Synaptobrevin-2; synaptobrevin 2; vesicle associated membrane protein 2
Gene ID : 6844
mRNA Refseq : NM_014232
Protein Refseq : NP_055047
UniProt ID : P63027
Chromosome Location : 17p13.1
MIM : 185881
Pathway : SNARE interactions in vesicular transport; Botulinum neurotoxicity; Diabetes pathways; Integration of energy metabolism; Membrane Trafficking; Synaptic Transmission
Function : protein binding

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