"CTSD" Related Products

Expand
Expand

Recombinant Human Cathepsin D

Cat. No.: CTSD-90H
Product Overview: Recombinant full length human Catheprsin D protein expressed inE.coli,48kDa.
Description: Cathepsin D is synthesized as a 54kDa precursor, which is proteolytically processed to an intermediate 48kDa single chain, which matures into more stable 34kDa and 14kDa two chain form. It is an estrogen-regulated lysosomal protease that has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix, and xonnective tissue. Because of its mitogenic and proteolytic activities, it has been implicated as a prognostic marker in many tumor types. Cathepsin D is expressed in epithelial cells as well as in macrophages.
Source: E.coli
Presentation: 5µg/50µl purified human Cathepsin D protein at 0.1mg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Applications: •ELISA •Inhibition Assays •Western Blotting
Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48kDa.
Activity: Not known.
Storage: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Gene Name: CTSD cathepsin D [ Homo sapiens ]
Synonyms: CTSD; cathepsin D; CPSD; CLN10; MGC2311; lysosomal aspartyl protease; lysosomal aspartyl peptidase; ceroid-lipofuscinosis, neuronal 10; EC 3.4.23.5; cathepsin D (lysosomal aspartyl protease);Cathepsin D light chain; Cathepsin D heavy chain
Gene ID: 1509
mRNA Refseq: NM_001909
Protein Refseq: NP_001900
MIM: 116840
UniProt ID: P07339
Chromosome Location: 11p15.5
Pathway: Lysosome
Function: aspartic-type endopeptidase activity; peptidase activity

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.