"IL3RA" Related Products

Recombinant Human Interleukin 3 Receptor, Alpha (Low Affinity)

Cat. No.: IL3RA-1644H
Description: Interleukin 3 receptor alpha (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a type I transmembrane protein that is expressed on the large majority of progenitor cells. IL-3R alpha function can be defined by the activity of its ligand interleukin-3. IL-3 is a multipotent cytokine that promotes the development of hemopoietic progenitors into cells of the erythroid, myeloid and lymphoid lineages.1CD123 may be a promising strategy for the preferential ablation of acute myelogenous leukemia (AML) cells.
Source: NSO Cells.
State Of Matter: Lyophilized.
Purity: >97% by SDS Page and analyzed by silver stain.
Endotoxin: <0.1 ng per 1 µg as determined by the LAL method.
Molecular Weight: The predicted molecular weight of Recombinant Human IL-3 sRα is Mr 33 kDa.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Gene Name: IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens ]
Synonyms: IL3RA; interleukin 3 receptor, alpha (low affinity); RP11-261P4.2; CD123; IL3R; IL3RAY; IL3RX; IL3RY; MGC34174; hIL-3Ra; CD123 antigen; Interleukin-3 receptor; interleukin 3 receptor, alpha; IL-3R-alpha; OTTHUMP00000022828; MGC34174
Gene ID: 3563
mRNA Refseq: NM_002183
Protein Refseq: NP_002174
MIM: 308385
UniProt ID: P26951
Chromosome Location: Xp22.3 or Yp11.3
Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Apoptosis; Hematopoietic cell lineage
Function: interleukin-3 receptor activity; receptor activity; protein binding

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