Recombinant Human TIMP Metallopeptidase Inhibitor 1
Cat.No. : | TIMP1-1688H |
- Specification
- Gene Information
- Related Products
Cat. No. : | TIMP1-1688H |
Description : | Tissue Inhibitor of Metalloproteinases 1, also known as TIMP1 is a widely expressed, secreted protein that functions primarily to inhibit members of a large family of metalloproteinases (MPs). Because of the ability of TIMP-1 to inhibit MPs, it functions in many of the same pathophysiological processes as these enzymes, e.g. wound healing, ovulation, angiogenesis, and cancer cell metastasis. TIMP-1 can also stimulate proliferation and cellular anabolic processes. TIMP-1 is a novel negative regulator of HGF activity during liver regeneration. Overexpression of TIMP-1 could promote renal interstitial fibrosis through the inflammatory pathway, which might be partly induced by upregulating ICAM-1. |
Molecular Weight : | The predicted molecular weight of Recombinant Human TIMP-1 is Mr 20.6 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 28-30 kDa. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | TIMP1 TIMP metallopeptidase inhibitor 1 [ Homo sapiens ] |
Synonyms : | TIMP1; TIMP metallopeptidase inhibitor 1; EPA; EPO; HCI; CLGI; TIMP; FLJ90373; tissue inhibitor of metalloproteinase 1; erythroid potentiating activity; fibroblast collagenase inhibitor; tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor); Tissue inhibitor of metalloproteinases; TIMP-1; Collagenase inhibitor; OTTHUMP00000023214; Erythroid-potentiating activity |
Gene ID : | 7076 |
mRNA Refseq : | NM_003254 |
Protein Refseq : | NP_003245 |
MIM : | 305370 |
UniProt ID : | P01033 |
Chromosome Location : | Xp11.3-p11.23 |
Function : | enzyme inhibitor activity; metalloendopeptidase inhibitor activity; protein binding |
Products Types
◆ Recombinant Protein | ||
TIMP1-001H | Recombinant Human TIMP1 Protein, MBP-tagged | +Inquiry |
Timp1-6436M | Active Recombinant Mouse Timp1 Protein, His-tagged | +Inquiry |
TIMP1-5733R | Recombinant Rat TIMP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TIMP1-0058H | Recombinant Human TIMP1 Protein | +Inquiry |
Timp1-01M | Recombinant Mouse Timp1 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
TIMP1-30840TH | Native Human TIMP1 | +Inquiry |
TIMP1-92H | Native Human TIMP-1 | +Inquiry |
TIMP1-91B | Active Native Bovine Thrombin | +Inquiry |
◆ Lysates | ||
TIMP1-2376MCL | Recombinant Mouse TIMP1 cell lysate | +Inquiry |
TIMP1-2678HCL | Recombinant Human TIMP1 cell lysate | +Inquiry |
TIMP1-1490RCL | Recombinant Rat TIMP1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket