Recombinant Human PRKDC

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Recombinant Human PRKDC

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Cat.No. : PRKDC-28357TH
Product Overview : Recombinant fragment corresponding to amino acids 4019-4128 of Human DNA PKcs with a N terminal proprietary tag; Predicted MWt 37.73 kDa including tag
Description : This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.
Protein length : 110 amino acids
Molecular Weight : 37.730kDa inclusive of tags
Source : Wheat germ
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : KMLKKGGSWI QEINVAEKNW YPRQKICYAK RKLAGANPAV ITCDELLLGH EKAPAFRDYV AVARGSKDHN IRAQEPESGL SEETQVKCLM DQATDPNILG RTWEGWEPWM
Sequence Similarities : Belongs to the PI3/PI4-kinase family.Contains 1 FAT domain.Contains 1 FATC domain.Contains 2 HEAT repeats.Contains 1 PI3K/PI4K domain.Contains 3 TPR repeats.
Gene Name : PRKDC protein kinase, DNA-activated, catalytic polypeptide [ Homo sapiens ]
Official Symbol : PRKDC
Synonyms : PRKDC; protein kinase, DNA-activated, catalytic polypeptide; HYRC, HYRC1; DNA-dependent protein kinase catalytic subunit; DNA PKcs; DNAPK; DNPK1; p350; XRCC7;
Gene ID : 5591
mRNA Refseq : NM_001081640
Protein Refseq : NP_001075109
MIM : 600899
Uniprot ID : P78527
Chromosome Location : 8q11
Pathway : BARD1 signaling events, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Class I PI3K signaling events mediated by Akt, organism-specific biosystem;
Function : ATP binding; DNA binding; DNA-dependent protein kinase activity; enzyme binding; nucleotide binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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