||Recombinant fusion protein, corresponding to amino acids 5-554 of Human ROCK2 with an N-terminal tag, expressed by baculovirus in Sf9 insect cells.
||The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
||Specific activity 350 nmol/min/mg.
||Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
||Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
||Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.Contains 1 AGC-kinase C-terminal domain.Contains 1 PH domain.Contains 1 phorbol-ester/DAG-type zinc finger.Contains 1 protein kinase domain.Contains 1 REM (Hr1) repeat.