"TDGF1" Related Products


Recombinant Human TDGF1, MBP

Cat. No.: TDGF1-2904H
Product Overview: Recombinant Human TDGF1 (1-188 aa) is expressed in E.Coli with MBP.
Description: Teratocarcinoma-derived growth factor 1 is the founding member of the EGF-CFC gene family, which is conserved among vertebrates. Proteins within this family contain a signal sequence, a characteristic EGF-like domain, a cysteine-rich region termed the cryptic (CFC) motif, and a hydrophobic C-terminus. It has been reported that Cripto-1 is O-fucosylated on Thr-88 and that this modification is required for the physical interaction with Nodal as well as for signalling activity. We have confirmed that teratocarcinoma-derived growth factor 1 is O-fucosylated at this site.
Source: E.Coli.
MW: 65835 Da.
Formulation: Lyophilized from a solution of phosphate buffered saline (PBS), pH 7.4 purified by affinity chromatography.
Application: ELISA, WB, Antibody Production, Protein array.
Synonyms: TDGF1; teratocarcinoma-derived growth factor 1; CR; CRGF; CRIPTO; Cripto-1; Epidermal growth factor-like cripto protein CR1; Cripto-1 growth factor
Gene ID: 6997
mRNA Refseq: NM_003212
Protein Refseq: NP_003203
MIM: 187395
UniProt ID: P13385
Chromosome Location: 3p21.31
Function: growth factor activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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