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Recombinant Human Serum Amyloid A1

Cat. No.: SAA1-2668H
Product Overview: Recombinant Human Serum Amyloid A1 is expressed inE. coli. MW=11.5 kDa.
Description: Serum amyloid A1 (SAA1) protein is made primarily in the liver and circulates in low levels in the blood. This protein appears to play a role in the immune system. Levels of this protein increase in the blood and other tissues under conditions of inflammation. SAA1 may help repair damaged tissues, acts as an antibacterial agent, and signal the migration of germ-fighting cells to sites of infection. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs.
Source: E. coli.
Reconstitution: Centrifuge the vial prior to opening. Reconstitute in 0.1% acetic acid to a concentration of 1μg/μl. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Activity: For most in vitro applications, apo-SAA exerts its biological activity in the concentration range of 10-50 μg/ml.
Storage: The lyophilized human apo-SAA is best-stored desiccated below 0oC. Reconstituted apo-SAA should be stored in working aliquots at -20°C.
Gene Name: SAA1 serum amyloid A1 [ Homo sapiens ]
Synonyms:
SAA1; serum amyloid A1; SAA; PIG4; TP53I4; MGC111216; tumor protein p53 inducible protein 4; MGC111216; Serum amyloid A protein; Amyloid protein A; Amyloid fibril protein AA; Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(2-102); Serum amyloid protein A(4-101); SAA2
Gene ID: 6288
mRNA Refseq: NM_000331
Protein Refseq: NP_000322
MIM: 104750
UniProt ID: P02735
Chromosome Location: 11p15.1
Function: G-protein-coupled receptor binding

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