"IL17C" Related Products

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Recombinant Human Interleukin 17C, Fc Chimera

Cat. No.: IL17C-280H
Product Overview: Recombinant Human Interleukin 17C is produced in mammalian cells andfused with fused with human IgG1Fc. IL-17C (C-terminus fused with human IgG1Fc) contains 408 amino acids with predicted MW 45.43 kDa x 2 (dimmer) and 14 cysteines (Fc has 6) with no N-link glycosylation site. It stimulates the release of tumor necrosis factor alpha and IL-1beta from the monocytic cell line THP-1.
Description: Interleukin-17 (IL-17, or IL-17A) is the founding member of a group of cytokines called the IL-17 family. IL-17A, was originally identified as a transcript from a rodent T-cell hybridoma by Rouvier et al. in 1993. Known as CTLA8 in rodents, IL-17 shows high homology to viral IL-17 encoded by an open reading frame of the T lymphotropic rhadinovirus Herpesvirus saimiri. To elicit its functions, IL-17 binds to a type I cell surface receptor called IL-17R of which there are at least three variants IL17RA, IL17RB, and IL17RC.
Source: Mammalian cells.
Purity: >90%.
Quantity: 2.0mg/2ml PBS.
Availability: Back order, one month for production.
Storage: -70°C.
Gene Name: IL17C interleukin 17C [ Homo sapiens ]
Synonyms: IL17C; interleukin 17C; CX2; IL-21; IL-17C; MGC126884; MGC138401; interleukin-17C; cytokine CX2
Gene ID: 27189
mRNA Refseq: NM_013278
Protein Refseq: NP_037410
MIM: 604628
UniProt ID: Q9P0M4
Chromosome Location: 16q24
Function: cytokine activity

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