Human Alpha-2-Macroglobulin
Cat.No. : | A2M-4176H |
Product Overview : | Human A2M is a tetrameric glycoprotein, produced in Human plasma and having a molecular mass of 725 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | A2M-4176H |
Description : | A2M is a serine proteases inhibitor, which inhibits coagulation by inactivating thrombin and Kallikrein, it inhibits fibrinolysis by inactivating plasmin and involved in insulin transport. A2M is a large plasma protein, which is produced by the liver. |
Source : | Human |
Host : | Human Plasma. |
Form : | Lyophilized from 0.02 M TRIS, 0.15 M NaCl and 0.1 M Sucrose, pH 8.0. |
Purity : | Greater than 96.0%. |
Physical Appearance : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Storage : | Human A2M although stable at room temperature for 3 weeks, should be stored between 2-8°C. |
Gene Name : | A2M alpha-2-macroglobulin [ Homo sapiens ] |
Official Symbol : | A2M |
Synonyms : | A2M; alpha-2-macroglobulin; CPAMD5; FWP007; S863-7; DKFZp779B086; alpha-2-macroglobulin; alpha-2-M; OTTHUMP00000196829; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 |
Gene ID : | 2 |
mRNA Refseq : | NM_000014 |
Protein Refseq : | NP_000005 |
MIM : | 103950 |
UniProt ID : | P01023 |
Chromosome Location : | 12p13 |
Pathway : | Complement and Coagulation Cascades; Formation of Fibrin Clot ; Formation of Platelet plug; HDL-mediated lipid transport; Hemostasis; IL6-mediated signaling events; Intrinsic Pathway; Lipid digestion; Lipoprotein metabolism; Metabolism of lipids and lipoproteins; Platelet Activation; Platelet degranulation; Rho GTPase cycle |
Function : | GTPase activator activity; enzyme binding; growth factor binding; interleukin-1 binding; interleukin-8 binding; protein binding; serine-type endopeptidase inhibitor activity; tumor necrosis factor binding |
Products Types
◆ Native Protein | ||
A2m-695R | Native Rat Alpha-2-Macroglobulin | +Inquiry |
A2m-367M | Native Mouse Alpha-2-Macroglobulin | +Inquiry |
◆ Lysates | ||
A2M-593HCL | Recombinant Human A2M cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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