Native Human Proteinase 3

Cat.No. : PRTN3-242H
Product Overview : Purified Native Human Azurophil Granules Proteinase 3
  • Specification
  • Gene Information
  • Related Products
  • Download
Description : Recent studies show a potential role for the serine protease PR3 in determining mortality and incidence of heart failure following AMI.PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. In human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. PR3 is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, as the major autoantigen of c-ANCA and is strongly expressed in lung tissue of patients with Wegener"s granulomatosis.
Source : Human Azurophil Granules
Species : Human
Form : Liquid
Molecular Mass : 29000
Purity : >96% by SDS-PAGE
Storage : Below -20 °C, Avoid repeat freeze-thaws.
Tag : Non
Gene Name : PRTN3 proteinase 3 [ Homo sapiens ]
Official Symbol : PRTN3
Synonyms : PRTN3; proteinase 3; myeloblastin; ACPA; AGP7; C ANCA; MBT; P29; PR 3; serine proteinase; neutrophil; Wegener granulomatosis autoantigen; NP-4; C-ANCA antigen; wegener autoantigen; leukocyte proteinase 3; neutrophil proteinase 4; azurophil granule protein
Gene ID : 5657
mRNA Refseq : NM_002777
Protein Refseq : NP_002768
MIM : 177020
UniProt ID : P24158
Chromosome Location : 19p13.3
Pathway : C-MYB transcription factor network, organism-specific biosystem;
Function : enzyme binding; peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


  • Reviews
  • Q&As

Customer Reviews (3)

Write a review

    Very good after-sales service to get my experiments going!


      The technician modified my experimental protocol so that my experiment went smoothly.


        The protein composition was stable and concentrated, allowing me to obtain satisfactory experimental results.

        Q&As (0)

        Ask a question

        Ask a Question for All PRTN3 Products

        Required fields are marked with *

        My Review for All PRTN3 Products

        Required fields are marked with *


        Inquiry Basket


        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /
        • Service lnquiry:

        Stay Updated on the Latest Bioscience Trends