Native Human Proteinase 3
Cat.No. : | PRTN3-242H |
Product Overview : | Purified Native Human Azurophil Granules Proteinase 3 |
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Description : | Recent studies show a potential role for the serine protease PR3 in determining mortality and incidence of heart failure following AMI.PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. In human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. PR3 is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, as the major autoantigen of c-ANCA and is strongly expressed in lung tissue of patients with Wegener"s granulomatosis. |
Source : | Human Azurophil Granules |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 29000 |
Purity : | >96% by SDS-PAGE |
Storage : | Below -20 °C, Avoid repeat freeze-thaws. |
Tag : | Non |
Gene Name : | PRTN3 proteinase 3 [ Homo sapiens ] |
Official Symbol : | PRTN3 |
Synonyms : | PRTN3; proteinase 3; myeloblastin; ACPA; AGP7; C ANCA; MBT; P29; PR 3; serine proteinase; neutrophil; Wegener granulomatosis autoantigen; NP-4; C-ANCA antigen; wegener autoantigen; leukocyte proteinase 3; neutrophil proteinase 4; azurophil granule protein |
Gene ID : | 5657 |
mRNA Refseq : | NM_002777 |
Protein Refseq : | NP_002768 |
MIM : | 177020 |
UniProt ID : | P24158 |
Chromosome Location : | 19p13.3 |
Pathway : | C-MYB transcription factor network, organism-specific biosystem; |
Function : | enzyme binding; peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity; |
Products Types
◆ Recombinant Protein | ||
PRTN3-7193M | Recombinant Mouse PRTN3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRTN3-252H | Recombinant Human PRTN3 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
PRTN3-1779H | Recombinant Human PRTN3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRTN3-2633H | Recombinant Human PRTN3 Protein, His-tagged | +Inquiry |
PRTN3-1996H | Recombinant Human PRTN3 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
PRTN3-01H | Native Human PRTN3 Protein | +Inquiry |
PRTN3-243H | Native Human Proteinase 3 Protein | +Inquiry |
◆ Lysates | ||
PRTN3-2797HCL | Recombinant Human PRTN3 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewVery good after-sales service to get my experiments going!
The technician modified my experimental protocol so that my experiment went smoothly.
The protein composition was stable and concentrated, allowing me to obtain satisfactory experimental results.
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