Recombinant Horse SAA1 Protein (1-110 aa), His-tagged

• Cat.No.: SAA1-2345H
• Product Overview: Recombinant Horse SAA1 Protein (1-110 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Full Length.

Specification

• Description: Major acute phase reactant. Apolipoprotein of the HDL complex.
• Source: Yeast
• Species: Horse
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 14.3 kDa
• Protein length: 1-110 aa
• AA Sequence: LLSFLGEAARGTWDMIRAYNDMREA NYIGADKYFHARGNYDAAKRGPGGA WAAKVISDARENFQRFTDRFSFGGS GRGAEDSRADQAANEWGRSGKDPNH FRPHGLPDKY
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: SAA1 serum amyloid A1 [ Equus caballus ]
• Official Symbol: SAA1
• Synonyms: SAA1; serum amyloid A1; serum amyloid A protein; SAA
• Gene ID: 100034017
• mRNA Refseq: NM_001163892
• Protein Refseq: NP_001157364
• UniProt ID: P19857

Reviews

06/05/2022

Gel electrophoresis consistently displayed well-defined bands, affirming the product's purity and reliability.

09/21/2018

The product's manufacturer went above and beyond to ensure our satisfaction, strengthening our trust in the brand.

09/15/2018

The value derived from the product's usage made the investment worthwhile, considering the insights acquired.

Q&As

Are there specific stimuli or triggers that induce the expression and secretion of SAA1, influencing its role in the acute-phase response?

Specific stimuli or triggers, such as infection or tissue damage, induce the expression and secretion of SAA1, influencing its role in the acute-phase response.

What diseases or conditions are associated with dysregulation or abnormal expression of SAA1, especially in the context of inflammatory disorders?

Dysregulation or abnormal expression of SAA1 is associated with various inflammatory disorders, including rheumatoid arthritis and atherosclerosis.

In which cellular compartments is SAA1 predominantly synthesized and secreted?

SAA1 is predominantly synthesized in the liver and secreted into the bloodstream, serving as a major acute-phase protein.

What is the primary role of Serum Amyloid A1 (SAA1) in cellular processes and acute-phase responses?

Serum Amyloid A1 (SAA1) plays a crucial role in cellular processes, primarily contributing to acute-phase responses and inflammatory reactions.

How does SAA1 contribute to inflammation, particularly in the context of acute-phase reactions?

SAA1 contributes to inflammation by actively participating in acute-phase reactions, amplifying the immune response during various challenges.

Are there therapeutic implications or potential targets related to SAA1 in diseases involving acute-phase responses and chronic inflammation?

There are potential therapeutic implications related to SAA1 in diseases involving acute-phase responses and chronic inflammation, making it a target for drug development.

How does SAA1 participate in modulating immune responses and influencing the progression of inflammatory conditions?

SAA1 actively modulates immune responses, influencing the progression of inflammatory conditions and contributing to tissue repair.