Recombinant Human ACTB Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: ACTB-074H
• Product Overview: ACTB MS Standard C13 and N15-labeled recombinant protein (NP_001092) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 41.6 kDa
• AA Sequence: MDDDIAALVVDNGSGMCKAGFAGDD APRAVFPSIVGRPRHQGVMVGMGQK DSYVGDEAQSKRGILTLKYPIEHGI VTNWDDMEKIWHHTFYNELRVAPEE HPVLLTEAPLNPKANREKMTQIMFE TFNTPAMYVAIQAVLSLYASGRTTG IVMDSGDGVTHTVPIYEGYALPHAI LRLDLAGRDLTDYLMKILTERGYSF TTTAEREIVRDIKEKLCYVALDFEQ EMATAASSSSLEKSYELPDGQVITI GNERFRCPEALFQPSFLGMESCGIH ETTFNSIMKCDVDIRKDLYANTVLS GGTTMYPGIADRMQKEITALAPSTM KIKIIAPPERKYSVWIGGSILASLS TFQQMWISKQEYDESGPSIVHRKCF TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ACTB actin beta [ Homo sapiens (human) ]
• Official Symbol: ACTB
• Synonyms: ACTB; actin beta; BRWS1; PS1TP5BP1; actin, cytoplasmic 1; I(2)-actin; PS1TP5-binding protein 1; beta cytoskeletal actin
• Gene ID: 60
• mRNA Refseq: NM_001101
• Protein Refseq: NP_001092
• MIM: 102630
• UniProt ID: P60709