Recombinant Human CD28 Protein (Asn19-Pro152), N-His-SUMO tagged, Animal-free, Carrier-free
Cat.No. : | CD28-322H |
Product Overview : | Recombinant Human CD28 Protein (Asn19-Pro152) with N-His-SUMO tag was expressed in HEK293 and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
Description : | CD28, a well-known costimulatory receptor expressed on T cells, is a type I transmembrane glycoprotein of the Ig superfamily. When the T cells receive the first signal delivered by APCs (antigen-presenting cells), it initiates signaling cascades, which favor T cell survival and proliferation. It has been demonstrated that patients with lung cancer who responded to PD-1 therapy had more CD28+ T cells, suggesting that CD28 may predict treatment response. |
Source : | HEK293 cell |
Species : | Human |
Tag : | N-His-SUMO |
Form : | Lyophilized |
Molecular Mass : | The protein has a calculated MW of 28.61 kDa. The protein migrates as 48-62 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Asn19-Pro152 |
Endotoxin : | < 1 EU/μg of the protein by the LAL method. |
Purity : | >95% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | CD28 CD28 molecule [ Homo sapiens (human) ] |
Official Symbol : | CD28 |
Synonyms : | CD28; CD28 molecule; CD28 antigen (Tp44); T-cell-specific surface glycoprotein CD28; T cell specific surface glycoprotein; CD28 antigen; Tp44; MGC138290; |
Gene ID : | 940 |
mRNA Refseq : | NM_001243077 |
Protein Refseq : | NP_001230006 |
MIM : | 186760 |
UniProt ID : | P10747 |
Products Types
◆ Recombinant Protein | ||
CD28-624M | Recombinant Mouse CD28 Protein | +Inquiry |
CD28-4376H | Recombinant Human CD28 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD28-1204C | Active Recombinant Cynomolgus CD28 protein(Met1-Pro152), hFc-tagged | +Inquiry |
CD28-0774H | Recombinant Human CD28 Protein, GST-Tagged | +Inquiry |
CD28-338H | Active Recombinant Human / Cynomolgus / Rhesus Monkey CD28 Protein, Fc & Avi-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
CD28-2002MCL | Recombinant Mouse CD28 cell lysate | +Inquiry |
CD28-2013HCL | Recombinant Human CD28 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1705 | CD28:B7-1[Biotinylated] Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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