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Recombinant Human CD4 Molecule (411-459)

Cat.No. : CD4-104H
Product Overview : Recombinant Human CD4produced inEscherichia Coli encoding amino acids 411-459.
  • Specification
  • Gene Information
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Cat. No. : CD4-104H
Description : CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes.
Source : Escherichia Coli.
Physical Appearance : Sterile filtered liquid.
Formulation : Recombinant Human CD4 protein at 100µg/ml in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.
Application and Suggested Dilutions : •ELISA •Inhibition Assays •Western Blotting
Characterization : On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48kDa.
Storage : Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.
Gene Name : CD4 molecule [ Homo sapiens ]
Synonyms : Gp55; HLA-2; L3 / T4; Ly-4; T cell antigen T4/LEU3; T4; sCD4; CD4mut; CD4; CD4 antigen; CD4 antigen (p55); CD4 molecule; CD4 receptor; T-cell surface antigen T4/Leu-3; CD4 molecule; 12pter-p12
Gene ID : 920
mRNA Refseq : NM_000616
Protein Refseq : NP_000607
MIM : 186940
UniProt ID : P01730
Chromosome Location : 12pter-p12
Pathway : Primary immunodeficiency; Antigen processing and presentation; Hematopoietic cell lineage; Cell adhesion molecules (CAMs); T cell receptor signaling pathway
Function : MHC class II protein binding; coreceptor activity; extracellular matrix structural constituent; glycoprotein binding; protein kinase binding; zinc ion binding; protein homodimerization activity; transmembrane receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.



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