Description : |
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
C-His-Avi |
Protein length : |
Lys26-Trp390 |
Conjugation/Label : |
Biotin |
Form : |
Lyophilised |
Endotoxin : |
Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg). |
Notes : |
FOR RESEARCH USE ONLY (RUO). |
Storage : |
The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade. |
Storage Buffer : |
Lyophilised from 0.2 μm filtered PBS solution pH 7.4. Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20 sec, 5K RPM |