CD47

  • Official Full Name

    CD47 molecule

  • Overview

    alphaVbeta3 is a type of integrin that is a receptor for vitronectin. It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed by platelets. Furthermore it is a receptor for phagocytosis on macrophages or dendritic cells. Inhibitors like etaracizumab may be used as antiangiogenics.
  • Synonyms

    CD47; CD47 molecule; CD47 antigen (Rh related antigen, integrin associated signal transducer), MER6; leukocyte surface antigen CD47; antigen identified by monoclonal 1D8; antigenic surface determinant protein OA3; CD47 glycoprotein; IAP; integrin associated protein; OA3; Rh related antigen; Rh-related antigen; integrin-associated protein; integrin-associated signal transducer; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); MER6;

  • Recombinant Proteins
  • GMP Proteins
  • Cell & Tissue Lysates
  • Chromatography Reagents
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Bovine
  • Canine
  • Chicken
  • Cynomolgus
  • Cynomolgus / Rhesus macaque
  • Cynomolgus monkey
  • Cynomolgus/Rhesus macaque
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
  • Rabbit
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Sus scrofa (Pig)
  • CHO cells
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • Human cells
  • Human Cells
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Mammalian Cells
  • Protein Conjugation
  • Sf9 Insect Cell
  • Wheat Germ
  • Avi|Fc|Biotin
  • C
  • hFc
  • His
  • mFc
  • 6×His
  • DDK
  • DDK|His
  • DYKDDDDK
  • Fc
  • Avi
  • His(C
  • ter)
  • GST
  • hIgG
  • His (Fc)
  • His|Avi
  • His|Flag|StrepII
  • His|HIgG
  • Flag
  • HlgG1 Fc
  • human|IgG1|Fc
  • IgG2a Fc
  • LEVLFQ
  • LIgG2b Fc
  • Mouse|IgG2a|Fc
  • N/A
  • N
  • RlgG Fc
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD47-7890H Active Recombinant Human CD47 protein, Fc/Avi-tagged, Biotinylated HEK293 Avi/Fc/Biotin Gln 19 - Pro 139
Human CD47-7891H Active Recombinant Human CD47 Protein, His-tagged, Biotinylated HEK293 His Gln 19 - Pro 139
Human CD47-5495H Active Recombinant Human CD47 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human CD47-556H Active Recombinant Human CD47 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Gln19-Pro139
Human CD47-051H Active Recombinant Human CD47 protein, Fc/Avi-tagged, CHO cells Fc/Avi Gln19-Pro139
Human CD47-101HG Active GMP Recombinant Human CD47 protein HEK293 DNA sequence encoding Human CD47(NCBI Reference Sequence: NP_942088.1) was expressed with His tag at the C-terminal.
Human CD47-2332H Recombinant Human CD47 protein(Met1-Pro139), hFc-tagged HEK293 C-hFc Met1-Pro139
Human CD47-7862H Recombinant Human CD47 protein(Gln19-Pro139), His-tagged HEK293 C-His Gln19-Pro139
Human CD47-7889H Recombinant Human CD47, Fc tagged Human Cell N/A
Human CD47-40H Recombinant Human CD47 protein, hIgG-His-tagged Insect Cell His/HIgG
Human CD47-7865H Recombinant Human CD47 protein(Met1-Pro139) HEK293 N/A Met1-Pro139
Human CD47-71H Recombinant Human CD47 protein, His-tagged Insect Cell His
Human CD47-835H Recombinant Human CD47 Protein, DDK/His-tagged HEK293 DDK/His
Human CD47-834H Recombinant Human CD47 Protein, Fc-tagged HEK293 Fc
Human CD47-90H Recombinant Human CD47 protein, T7/His-tagged E.coli T7/His
Human CD47-333H Recombinant CD47 protein, His/Avi-tagged HEK293 His/Avi 121
Human CD47-836H Recombinant Human CD47 Protein, DDK-tagged Sf9 Insect Cell DDK
Human CD47-0825H Recombinant Human CD47 Protein Wheat Germ N/A
Human CD47-837H Recombinant Human CD47 Protein, Fc-tagged HEK293 Fc
Human CD47-0826H Recombinant Human CD47 Protein, His-Flag-StrepII-Tagged Human Cell His/Flag/StrepII
Human CD47-0827H Recombinant Human CD47 Protein, GST-Tagged Wheat Germ GST
Human CD47-850HCL Recombinant Human CD47 cell lysate Human Cell N/A
Human CD47-7889HAF488 Recombinant Human CD47 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 362
Human CD47-14H Active Recombinant Human CD47 Protein, hIgG/His-tagged Insect Cell hIgG/His 19-141
Human CD47-7865HB Recombinant Human CD47 protein, LEVLFQ-tagged, Biotinylated HEK293 LEVLFQ
Human CD47-152H Recombinant Human CD47 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human CD47-3292H Recombinant Human CD47 protein, His-tagged, low endotoxin HEK293 His Gln19-Pro139
Human CD47-7865HAF555 Recombinant Human CD47 Protein, Alexa Fluor 555 conjugated HEK293 LEVLFQ Met1-Pro139, 128
Human CD47-151H Recombinant Human CD47 Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human CD47-7865HAF488 Recombinant Human CD47 Protein, Alexa Fluor 488 conjugated HEK293 LEVLFQ Met1-Pro139, 128
Human CD47-527H Recombinant Human CD47 protein, Fc-tagged (HPLC-verified) HEK293 human/IgG1/Fc Gln19-Pro139
Human CD47-7889HAF555 Recombinant Human CD47 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 362
Human CD47-33H Recombinant Human CD47 Protein (ECD), Fc-His-tagged(C-ter) HEK293 Fc-His(C-ter) Gln19-Pro139
Human CD47-640H Recombinant Human CD47 Protein, Fc-tagged HEK293 Fc 323
Human CD47-555H Recombinant Human CD47 Protein (Met1-Pro139), His-tagged Insect Cell His Met1-Pro139
Human CD47-7865HAF647 Recombinant Human CD47 Protein, Alexa Fluor 647 conjugated HEK293 LEVLFQ Met1-Pro139, 128
Human CD47-347H Active Recombinant Human CD47 Protein, LIgG2b Fc-tagged, low endotoxin HEK293 LIgG2b Fc Gln 19 - Pro 139
Human CD47-1276H Recombinant Human CD47 Protein (Met1-Glu141), C-His tagged Mammalian cells C-His Met1-Glu141
Human CD47-2153H Recombinant Human CD47 Protein, His-tagged E.coli N-His Ala18-Glu141
Human CD47-7889HAF647 Recombinant Human CD47 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 362
Human CD47-348H Recombinant Human CD47 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc 121
Human CD47-508H Recombinant Human CD47 Protein (Gln19-Gln141, Val198-Ala207, Ser257-Gly268), C-mFc and 6×His-tagged HEK293 C-mFc and 6×His Gln19-Gln141, Val198-Ala207, Ser257-Gly268
Human CD47-2784H Recombinant Human CD47 Protein, His-tagged, OVA Conjugated Protein Conjugation N-His Glu308-Glu323
Human CD47-199H Recombinant Human CD47 Protein, C-His-tagged E.coli C-His
Human CD47-2186H Active Recombinant Human CD47 protein, His-tagged HEK293 His Met1-Pro139
Human CD47-0252H Recombinant Human CD47 protein, Biotinylated HEK293 N/A Met1-Pro139
Human CD47-2993HF Recombinant Full Length Human CD47 Protein In Vitro Cell Free System 99 amino acids
Human CD47-1239H Recombinant Human CD47 Protein (Gln19-Pro139), N-His tagged E.coli N-His Gln19-Pro139
Human CD47-987M PE-labeled CD47 protein-coupled magnetic Beads
Human CD47-7865HF Recombinant Human CD47 Protein, FITC conjugated HEK293 LEVLFQ Met1-Pro139, 128
Human CD47-2996HF Recombinant Full Length Human CD47 Protein, GST-tagged In Vitro Cell Free System GST 323 amino acids
Human CD47-7889HF Recombinant Human CD47 Protein, Fc-tagged, FITC conjugated HEK293 Fc 362
Human CD47-641H Recombinant Human CD47 Protein, IgG2a Fc-tagged HEK293 IgG2a Fc 323
Human CD47-645H Recombinant Human CD47 Protein, His and Avi-tagged HEK293 His and Avi 323
Human CD47-639H Recombinant Human CD47 Protein HEK293 323
Human CD47-0989M Active CD47 protein-coupled magnetic Beads HEK293 Gln 19 - Pro 139
Mouse Cd47-645M Active Recombinant Mouse Cd47 protein, Fc-tagged Mammalian cells Fc Gln19-Pro158
Mouse Cd47-647MF Recombinant Mouse Cd47 Protein, His-tagged, FITC conjugated HEK293 His Met1-Lys140, 133
Mouse CD47-3095M Recombinant Mouse Cd47 protein, Fc-tagged HEK293 Fc Gln19-Pro158
Mouse CD47-3094M Recombinant Mouse Cd47 protein, His-tagged HEK293 His Gln19-Pro158
Mouse Cd47-5727M Recombinant Mouse Cd47 protein, His-tagged E.coli His Ala18~Gly219
Mouse Cd47-646M Recombinant Mouse Cd47 protein, Fc-tagged HEK293 human/IgG1/Fc 122
Mouse Cd47-18M-B Recombinant Mouse Cd47 Protein Pre-coupled Magnetic Beads HEK293
Mouse CD47-382M Active Recombinant Mouse CD47 protein, His-tagged HEK293 His Gln19-Lys140
Mouse CD47-892M Recombinant Mouse CD47 Protein (Met1-Lys140), RlgG Fc-tagged HEK293 RlgG Fc Met1-Lys140
Mouse CD47-384M Recombinant Mouse CD47 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc 122
Mouse Cd47-647MAF647 Recombinant Mouse Cd47 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His Met1-Lys140, 133
Mouse CD47-0248M Recombinant Mouse CD47 protein, Fc -tagged HEK293 Fc Met1-Lys140
Mouse CD47-380M Recombinant Mouse CD47 protein (Met1-Lys140) HEK293
Mouse Cd47-5707M Recombinant Mouse Cd47 Protein (Met1-Ile162), C-His tagged Mammalian cells C-His Met1-Ile162
Mouse Cd47-647MAF555 Recombinant Mouse Cd47 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His Met1-Lys140, 133
Mouse CD47 -0245M Recombinant Mouse CD47 protein HEK293 N/A Met1-Lys140
Mouse CD47-642M Recombinant Mouse CD47 Protein, Fc-tagged HEK293 Fc 303
Mouse Cd47-18M Recombinant Mouse Cd47 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Cd47-647MAF488 Recombinant Mouse Cd47 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His Met1-Lys140, 133
Rat CD47-1255R Recombinant Rat CD47 Protein Mammalian Cell His
Rat Cd47-7480R Recombinant Rat Cd47 protein, Fc-tagged HEK293 human/IgG1/Fc Gln19-Lys140
Rat Cd47-8767R Active Recombinant Rat Cd47, His tagged HEK293 His Met1-Lys140
Rat CD47-1363RCL Recombinant Rat CD47 cell lysate Human Cell N/A
Rat CD47-913R Recombinant Rat CD47 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Cd47-8767RF Recombinant Rat Cd47 Protein, His-tagged, FITC conjugated HEK293 His 133
Rat Cd47-8767RAF488 Recombinant Rat Cd47 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 133
Rat Cd47-7480RAF555 Recombinant Rat Cd47 Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 hFc Gln19-Lys140
Rat Cd47-7480RAF488 Recombinant Rat Cd47 Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 hFc Gln19-Lys140
Rat Cd47-8767RAF555 Recombinant Rat Cd47 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 133
Rat Cd47-7480RAF647 Recombinant Rat Cd47 Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 hFc Gln19-Lys140
Rat Cd47-8767RAF647 Recombinant Rat Cd47 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 133
Rat CD47-913R-B Recombinant Rat CD47 Protein Pre-coupled Magnetic Beads HEK293
Rat Cd47-7480RF Recombinant Rat Cd47 Protein, hFc-tagged, FITC conjugated HEK293 hFc Gln19-Lys140
Rat CD47-644R Recombinant Rat CD47 Protein, Fc-tagged HEK293 Fc 303
Rabbit Cd47-70R Recombinant Rabbit Cd47 protein, Fc-tagged HEK293 human/IgG1/Fc Gln19-Glu139
Rabbit CD47-643R Recombinant Rabbit CD47 Protein, Fc-tagged HEK293 Fc 321
Bos taurus (Bovine) RFL25841BF Recombinant Full Length Bovine Leukocyte Surface Antigen Cd47(Cd47) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (19-303)
Bovine CD47-112B Recombinant Bovine CD47 Protein, His-tagged Mammalian Cells His Gln19 - Asn140
Bovine CD47-1B-B Recombinant Bovine CD47 Protein Pre-coupled Magnetic Beads HEK293
Bovine CD47-113B Recombinant Bovine CD48 Protein, Fc-tagged Mammalian Cells Fc Gln19 - Asn140
Bovine CD47-1B Recombinant Bovine CD47 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Canine CD47-862C Recombinant Canine CD47 protein, His-tagged HEK293 His Gln19-Asn140
Cynomolgus CD47-1017C Recombinant Cynomolgus CD47 Protein (Met1-Asn142), HlgG1 Fc-tagged HEK293 HlgG1 Fc Met1-Asn142
Cynomolgus / Rhesus macaque CD47-1946C Active Recombinant Cynomolgus / Rhesus macaque CD47 protein, Fc-tagged HEK293 Fc Gln 19 - Glu 141
Cynomolgus / Rhesus macaque CD47-679C Active Recombinant Cynomolgus / Rhesus macaque CD47 protein, His-tagged HEK293 His Gln 19 - Glu 141
Cynomolgus monkey CD47-638C Recombinant Cynomolgus monkey CD47 Protein, Fc-tagged HEK293 Fc 307
Cynomolgus/Rhesus macaque CD47-745C Recombinant Cynomolgus/Rhesus macaque CD47 protein, Fc-tagged HEK293 human/IgG1/Fc Gln4-Glu126
Cynomolgus/Rhesus macaque CD47-346C Recombinant Cynomolgus/Rhesus macaque CD47 protein, His-tagged HEK293 His 123
Cynomolgus/Rhesus macaque CD47-674C Recombinant Cynomolgus/Rhesus macaque CD47 protein, His-tagged HEK293 His Met1-Asn142
Mus musculus (Mouse) RFL14932MF Recombinant Full Length Mouse Leukocyte Surface Antigen Cd47(Cd47) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (19-303)
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RFL31430PF Recombinant Full Length Pongo Abelii Leukocyte Surface Antigen Cd47(Cd47) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (19-323)
Rattus norvegicus (Rat) RFL27649RF Recombinant Full Length Rat Leukocyte Surface Antigen Cd47(Cd47) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (19-303)
Rhesus Macaque CD47-743R Recombinant Rhesus monkey CD47 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CD47-745R Recombinant Rhesus Macaque CD47(Gln19-Glu141) Protein, N-6*His-Flag-tagged HEK293 His-Flag
Rhesus Macaque CD47-569R-B Recombinant Rhesus Macaque CD47 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CD47-569R Recombinant Rhesus Macaque CD47 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Sus scrofa (Pig) RFL17555SF Recombinant Full Length Pig Leukocyte Surface Antigen Cd47(Cd47) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (19-303)
Chicken CD47-1207C Recombinant Chicken CD47 Mammalian Cell His
Kit-1706 CD47:SIRP-α[Biotinylated] Inhibitor Screening Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CD47 involved in several pathways and played different roles in them. We selected most pathways CD47 participated on our site, such as ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD47 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ECM-receptor interactionCOL1A1;ITGB4;COL27A1B;COL11A2;VTNA;IBSP;COL4A1;SV2A;THBS2

CD47 has several biochemical functions, for example, protein binding, thrombospondin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CD47 itself. We selected most functions CD47 had, and list some proteins which have the same functions with CD47. You can find most of the proteins on our site.

Function Related Protein
protein bindingPTK6;RAB14;ELN;WNK1;CDC20B;CASP2;SOCS1;KLF5;NUMB
thrombospondin receptor activityF2;CD47;SDC4

CD47 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD47 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD47.

SYNE4; SIRPG; b3xyc5_sollc

Research Area

Related articles

Banerjee, R; Khandelwal, S; et al. CD47 regulates the phagocytic clearance and replication of the Plasmodium yoelii malaria parasite. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:3062-3067(2015).
Feng, MY; Chen, JY; et al. Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:2145-2150(2015).
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