Recombinant Human FGF23 Protein, His&GST-tagged
|Product Overview :||Recombinant Human FGF23 Protein (Tyr25-Ile251) with N-His&GST tag was expressed in E. coli.|
- Gene Information
- Related Products
|Description :||This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).|
|Source :||E. coli|
|Form :||Freeze-dried powder|
|Molecular Mass :||Predicted Molecular Mass: 54.9 kDa
Accurate Molecular Mass: 58 kDa
|Protein length :||Tyr25-Ile251|
|Purity :||> 80%|
|Applications :||Positive Control; Immunogen; SDS-PAGE; WB.|
|Stability :||The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.|
|Storage :||Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.|
|Storage Buffer :||PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.|
|Reconstitution :||Reconstitute in PBS or others.|
|Gene Name :||FGF23 fibroblast growth factor 23 [ Homo sapiens (human) ]|
|Official Symbol :||FGF23|
|Synonyms :||FGF23; fibroblast growth factor 23; ADHR; FGFN; HYPF; HFTC2; HPDR2; PHPTC; fibroblast growth factor 23; phosphatonin; tumor-derived hypophosphatemia inducing factor|
|Gene ID :||8074|
|mRNA Refseq :||NM_020638|
|Protein Refseq :||NP_065689|
|UniProt ID :||Q9GZV9|
|◆ Recombinant Protein|
|FGF23-036H||Active Recombinant Human FGF23 Protein||+Inquiry|
|FGF23-684H||Recombinant Human FGF23 Protein, His-tagged||+Inquiry|
|FGF23-908H||Recombinant Human FGF23 Protein, His (Fc)-Avi-tagged||+Inquiry|
|FGF23-1014H||Recombinant Human FGF23 Protein (Y25-R179), His tagged||+Inquiry|
|FGF23-1990R||Recombinant Rat FGF23 Protein, His (Fc)-Avi-tagged||+Inquiry|
|FGF23-6241HCL||Recombinant Human FGF23 293 Cell Lysate||+Inquiry|
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (7)Ask a question
FGF23 levels are elevated in chronic kidney disease, contributing to mineral imbalance.
High FGF23 levels are associated with increased cardiovascular risk.
It decreases renal phosphate reabsorption and 1,25-dihydroxyvitamin D production.
Mutations in FGF23 or related proteins can lead to dysregulated phosphate metabolism.
Strategies include phosphate binders and FGF23 antibodies to manage elevated FGF23 levels.
FGF23 is primarily produced in bone.
FGF23 regulates phosphate and vitamin D metabolism.
Customer Reviews (3)Write a review
Excellent results, high purity. -
Reliable and effective product. -
Quick delivery, product works. -
Ask a Question for All FGF23 Products
Required fields are marked with *
My Review for All FGF23 Products
Required fields are marked with *