Description : |
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
59.7 kDa |
AA Sequence : |
MELDLSPPHLSSSPEDLCPAPGTPP GTPRPPDTPLPEEVKRSQPLLIPTT GRKLREEERRATSLPSIPNPFPELC SPPSQSPILGGPSSARGLLPRDASR PHVVKVYSEDGACRSVEVAAGATAR HVCEMLVQRAHALSDETWGLVECHP HLALERGLEDHESVVEVQAAWPVGG DSRFVFRKNFAKYELFKSSPHSLFP EKMVSSCLDAHTGISHEDLIQNFLN AGSFPEIQGFLQLRGSGRKLWKRFF CFLRRSGLYYSTKGTSKDPRHLQYV ADVNESNVYVVTQGRKLYGMPTDFG FCVKPNKLRNGHKGLRIFCSEDEQS RTCWLAAFRLFKYGVQLYKNYQQAQ SRHLHPSCLGSPPLRSASDNTLVAM DFSGHAGRVIENPREALSVALEEAQ AWRKKTNHRLSLPMPASGTSLSAAI HRTQLWFHGRISREESQRLIGQQGL VDGLFLVRESQRNPQGFVLSLCHLQ KVKHYLILPSEEEGRLYFSMDDGQT RFTDLLQLVEFHQLNRGILPCLLRH CCTRVALTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |