| Description : |
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
199.3 kDa |
| AA Sequence : |
MADERKDEAKAPHWTSAPLTEASAH SHPPEIKDQGGAGEGLVRSANGFPY REDEEGAFGEHGSQGTYSNTKENGI NGELTSADRETAEEVSARIVQVVTA EAVAVLKGEQEKEAQHKDQTAALPL AAEETANLPPSPPPSPASEQTVTVE EDLLTASKMEFHDQQELTPSTAEPS DQKEKESEKQSKPGEDLKHAALVSQ PETTKTYPDKKDMQGTEEEKAPLAL FGHTLVASLEDMKQKTEPSLVVPGI DLPKEPPTPKEQKDWFIEMPTEAKK DEWGLVAPISPGPLTPMREKDVFDD IPKWEGKQFDSPMPSPFQGGSFTLP LDVMKNEIVTETSPFAPAFLQPDDK KSLQQTSGPATAKDSFKIEEPHEAK PDKMAEAPPSEAMTLPKDAHIPVVE EHVMGKVLEEEKEAINQETVQQRDT FTPSGQEPILTEKETELKLEEKTTI SDKEAVPKESKPPKPADEEIGIIQT STEHTFSEQKDQEPTTDMLKQDSFP VSLEQAVTDSAMTSKTLEKAMTEPS ALIEKSSIQELFEMRVDDKDKIEGV GAATSAELDMPFYEDKSGMSKYFET SALKEEATKSIEPGSDYYELSDTRE SVHESIDTMSPMHKNGDKEFQTGKE SQPSPPAQEAGYSTLAQSYPSDLPE EPSSPQERMFTIDPKVYGEKRDLHS KNKDDLTLSRSLGLGGRSAIEQRSM SINLPMSCLDSIALGFNFGRGHDLS PLASDILTNTSGSMDEGDDYLPATT PALEKAPCFPVESKEEEQIEKVKAT GEESTQAEISCESPFLAKDFYKNGT VMAPDLPEMLDLAGTRSRLASVSAD AEVARRKSVPSETVVEDSRTGLPPV TDENHVIVKTDSQLEDLGYCVFNKY TVPLPSPVQDSENLSGESGTFYEGT DDKVRRDLATDLSLIEVKLAAAGRV KDEFSVDKEASAHISGDKSGLSKEF DQEKKANDRLDTVLEKSEEHADSKE HAKKTEEAGDEIETFGLGVTYEQAL AKDLSIPTDASSEKAEKGLSSVPEI AEVEPSKKVEQGLDFAVQGQLDVKI SDFGQMASGLNIDDRRATELKLEAT QDMTPSSKAPQEADAFMGVESGHMK EGTKVSETEVKQKVAKPDLVHQEAV DKEESYESSGEHESLTMESLKADEG KKETSPESSLIQDEIAVKLSVEIPC PPAVSEADLATDERADVQMEFIQGP KEESKETPDISITPSDVAEPLHETI VSEPAEIQSEEEEIEAQGEYDKLLF RSDTLQITDLGVSGAREEFVETCPS EHKGVIESVVTIEDDFITVVQTTTD EGESGSHSVRFAALEQPEVERRPSP HDEEEFEVEEAAEAQAEPKDGSPEA PASPEREEVALSEYKTETYDDYKDE TTIDDSIMDADSLWVDTQDDDRSIM TEQLETIPKEEKAEKEARRSSLEKH RKEKPFKTGRGRISTPERKVAKKEP STVSRDEVRRKKAVYKKAELAKKTE VQAHSPSRKFILKPAIKYTRPTHLS CVKRKTTAAGGESALAPSVFKQAKD KVSDGVTKSPEKRSSLPRPSSILPP RRGVSGDRDENSFSLNSSISSSARR TTRSEPIRRAGKSGTSTPTTPGSTA ITPGTPPSYSSRTPGTPGTPSYPRT PHTPGTPKSAILVPSEKKVAIIRTP PKSPATPKQLRLINQPLPDLKNVKS KIGSTDNIKYQPKGGQVQIVTKKID LSHVTSKCGSLKNIGHRPGGGRVKI ESVKLDFKEKAQAKVGSLDNAHHVP GGGNVKIDSQKLNFREHAKARVDHG AEIITQSPGRSSVASPRRLSNVSSS GSINLLESPQLATLAEDVTAALAKQ GLTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
