Active Recombinant Human PDGFD protein
Cat.No. : | PDGFD-24H |
Product Overview : | Recombinant Human PDGFD was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rβ homodimers and PDGF Rα/β heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing. |
Source : | CHO |
Species : | Human |
Form : | Lyophilized after extensive dialysis against PBS. |
Bio-activity : | ED50 < 5 μg/ml, measured in a cell proliferation assay using 3T3 cells. |
Molecular Mass : | 19-21 kDa, observed by reducing SDS-PAGE. |
AA Sequence : | SYHDRKSKVD LDRLNDDAKR YSCTPRNYSV NIREELKLANVVFFPRCLLV QRCGGNCGCG TVNWRSCTCN SGKTVKKYHEVLQFEPGHIK RRGRAKTMAL VDIQLDHHER CDCICSSRPPR |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 95% as analyzed by SDS-PAGE. |
Storage : | Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80 centigradefrom date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4 centigradeor up to 2 months at -20°C. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/ml. |
Gene Name : | PDGFD platelet derived growth factor D [ Homo sapiens ] |
Official Symbol : | PDGFD |
Synonyms : | PDGFD; platelet derived growth factor D; platelet-derived growth factor D; IEGF; MSTP036; SCDGF B; spinal cord derived growth factor B; PDGF-D; iris-expressed growth factor; spinal cord-derived growth factor B; spinal cord-derived growth factor-B; SCDGFB; SCDGF-B; MGC26867; |
Gene ID : | 80310 |
mRNA Refseq : | NM_025208 |
Protein Refseq : | NP_079484 |
MIM : | 609673 |
UniProt ID : | Q9GZP0 |
Chromosome Location : | 11q22.3 |
Pathway : | Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Gap junction, organism-specific biosystem; Gap junction, conserved biosystem; Melanoma, organism-specific biosystem; Melanoma, conserved biosystem; |
Function : | growth factor activity; |
Products Types
◆ Recombinant Protein | ||
PDGFD-209P | Active Recombinant Human PDGFDD Protein | +Inquiry |
PDGFD-097H | Active Recombinant Human PDGFD Protein | +Inquiry |
PDGFD-4471H | Recombinant Human PDGFD Protein, His (Fc)-Avi-tagged | +Inquiry |
PDGFD-6596M | Recombinant Mouse PDGFD Protein, His (Fc)-Avi-tagged | +Inquiry |
PDGFD-3999R | Recombinant Rat PDGFD Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PDGFD-3335HCL | Recombinant Human PDGFD 293 Cell Lysate | +Inquiry |
PDGFD-3336HCL | Recombinant Human PDGFD 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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