Recombinant Human Tau-441 protein, phosphorylated

• Cat.No.: MAPT-38H
• Product Overview: Recombinant full length human tag-free Tau-441 was co-expressed with DYRK1A in E. coli cells. The Tau-441 was phosphorylated by DYRK1A in vivo and in vitro prior to the final chromatography purification.

Specification

• Source: E. coli
• Species: Human
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~68~71 kDa
• Purity: >95% by densitometry
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.2 ug/ul

Gene Information

• Gene Name: MAPT microtubule-associated protein tau [ Homo sapiens ]
• Official Symbol: MAPT
• Synonyms: MAPT;FLJ31424; FTDP 17; MSTD; MTBT1; MTBT2; PPND; tau; TAU; DDPAC; MAPTL; FTDP-17
• Gene ID: 4137
• mRNA Refseq: NM_001123066
• Protein Refseq: NP_001116538
• MIM: 157140
• UniProt ID: P10636
• Chromosome Location: 17q21
• Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Caspase-mediated cleavage of cytoskeletal proteins, organism-specific biosystem; IL-6 Signaling Pathway, organism-specific biosystem
• Function: SH3 domain binding; apolipoprotein E binding; enzyme binding; lipoprotein particle binding; microtubule binding; protein binding; structural constituent of cytoskeleton