Recombinant Mouse Ldhb Protein, MYC/DDK-tagged
Cat.No. : | Ldhb-1306M |
Product Overview : | Purified recombinant protein of full-length mouse lactate dehydrogenase B (Ldhb), with C-terminal MYC/DDK tag, was expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have also been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes 1 and 19. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 37 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 µg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Ldhb lactate dehydrogenase B [ Mus musculus (house mouse) ] |
Official Symbol : | Ldhb |
Synonyms : | Ldhb; lactate dehydrogenase B; Ldh2; H-Ldh; LDH-B; LDH-H; Ldh-2; AI790582; L-lactate dehydrogenase B chain; LDH heart subunit; lactate dehydrogenase 2, B chain; EC 1.1.1.27 |
Gene ID : | 16832 |
mRNA Refseq : | NM_008492 |
Protein Refseq : | NP_032518 |
UniProt ID : | P16125 |
Products Types
◆ Recombinant Protein | ||
LDHB-3026R | Recombinant Rat LDHB Protein, His (Fc)-Avi-tagged | +Inquiry |
LDHB-5021M | Recombinant Mouse LDHB Protein, His (Fc)-Avi-tagged | +Inquiry |
LDHB-424H | Recombinant Human LDHB Protein, MYC/DDK-tagged | +Inquiry |
LDHB-2309R | Recombinant Rhesus Macaque LDHB Protein, His (Fc)-Avi-tagged | +Inquiry |
Ldhb-1817M | Recombinant Mouse Ldhb protein, His-tagged | +Inquiry |
◆ Native Protein | ||
LDH2-123H | Active Native Human Lactate Dehydrogenase 2 | +Inquiry |
LDH2-220H | Active Native Human Lactate Dehydrogenase 2 | +Inquiry |
◆ Lysates | ||
LDHB-4788HCL | Recombinant Human LDHB 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0510 | Lactate Dehydrogenase B (LDHB) Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, LDHB dysregulation is associated with heart conditions like myocardial infarction (heart attack) and heart failure.
While LDHB-related diseases can affect anyone, some genetic predispositions may heighten the risk in certain ethnic groups.
It plays a role in various physiological processes and has implications in disease states.
In certain cancers, elevated LDHB levels promote tumor growth by supporting the Warburg effect, where cancer cells use glycolysis even in the presence of oxygen.
Targeting LDHB shows promise in inhibiting cancer growth, and there's ongoing research in developing drugs that target this enzyme.
Customer Reviews (3)
Write a reviewI highly endorse the utilization of the LDHB Protein for researchers seeking a superior protein solution that not only meets their experimental needs but also benefits from the exceptional technical support provided by the manufacturer.
Their expertise has proven instrumental in overcoming obstacles and has greatly contributed to the success of my research endeavors.
Their team of experts has been extremely helpful in addressing any concerns or queries I encountered during my experiments.
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