Recombinant Mouse Spr Protein, Myc/DDK-tagged
Cat.No. : | Spr-6107M |
Product Overview : | Purified recombinant protein of mouse full-length sepiapterin reductase (cDNA clone MGC:13710 IMAGE:4219245), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | Ubiquitous expression in kidney adult (RPKM 25.9), liver adult (RPKM 22.1) and 27 other tissues. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 27.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Spr sepiapterin reductase [ Mus musculus (house mouse) ] |
Official Symbol : | Spr |
Synonyms : | Spr; sepiapterin reductase; Gm10328; AA409688; sepiapterin reductase; EC 1.1.1.153 |
Gene ID : | 20751 |
mRNA Refseq : | NM_011467 |
Protein Refseq : | NP_035597 |
UniProt ID : | Q91XH5 |
Products Types
◆ Recombinant Protein | ||
SPR-681H | Recombinant Human SPR Protein, His/GST-tagged | +Inquiry |
Spr-205M | Recombinant Mouse Spr Protein, His-tagged | +Inquiry |
SPR-0242H | Recombinant Human SPR Protein (M1-K261), His tagged | +Inquiry |
Spr-682M | Recombinant Mouse Spr Protein, His-tagged | +Inquiry |
SPR-2090H | Recombinant Human SPR Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SPR-1499HCL | Recombinant Human SPR 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionStudying the biological function of SPR proteins requires a variety of experimental techniques and methods, such as cell biology, molecular biology, biochemistry and genomics. By observing gene expression, cell proliferation, signal transduction and other indicators, the biological function of SPR protein in cells can be evaluated.
With the in-depth understanding of the structure and function of SPR protein, the drug development and application of SPR protein will be more extensive in the future. For example, the development of drugs that target the SPR protein may be used to treat tumors, autoimmune diseases, and neurological diseases. In addition, understanding the biological function of SPR proteins may also be useful for research in other areas of science.
SPR proteins have multiple domains, including calcium-binding domains, kinase domains, and regulatory domains. Among them, the calcium ion binding domain can bind to calcium ions, the kinase domain can phosphorylate downstream proteins, and the regulatory domain can regulate the activity and stability of proteins.
SPR proteins can interact with a variety of transcription factors, such as NF-kB, AP-1, and CREB. Once interacting with these transcription factors, SPR proteins can regulate gene transcription and expression, influencing the biological behavior of cells.
Due to the important role of SPR protein in cell signal transduction and gene expression regulation, drug development targeting SPR protein is of great significance. At present, some drugs targeting SPR proteins have entered clinical trials for the treatment of some human diseases.
During cell signaling, SPR proteins can interact with G protein-coupled receptors (GPCRs) and are activated by GPCRs. Once activated, SPR proteins can phosphorylate downstream proteins such as MAPK and AKT to further regulate intracellular signal transduction.
Customer Reviews (3)
Write a reviewThe production process of SPR is very environmentally friendly, using clean production technology and green raw materials, so that the production process does not emit any harmful substances.
This reproducibility of SPR is very good, and the results can be highly consistent in every experiment or application, which proves its excellent stability and reliability.
This short half-life and high clearance of SPR provide new ideas and methods for the treatment of tumors, infection and other diseases.
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