Recombinant Rabbit IL17 Protein, His-tagged

PRODUCTS

Home / Products / Recombinant Rabbit IL17 Protein, His-tagged

Recombinant Rabbit IL17 Protein, His-tagged

IL17A Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : IL17A-441R
Product Overview : Recombinant Rabbit IL17A (XP_002714544.1) (Gly24-Ala153) was expressed with an initial Met.
Description : IL17, also known as IL17a, is a cytokine belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological pr centigradeesses including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (mon centigradeytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. The IL-17 family of cytokines includes six members, IL-17/IL-17A, IL-17B, IL-17C, IL-17D, IL-17E/IL-25, and IL-17F, which are produced by multiple cell types. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are ass centigradeiated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Source : E. coli
Species : Rabbit
Tag : His
Predicted N Terminal : Met
Form : Lyophilized from sterile PBS, pH, 7.4. Normally 5 %- 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized rabbit IL17a at 10μg/mL (100μL/well) can bind rat IL17RA-Fc3, the EC50 of rat IL17RA-Fc3 is 1-30 ng/mL.
Molecular Mass : The recombinant rabbit IL17A consists of 131 amino acids and predicts a molecular mass of 15.1 kDa
Protein length : Gly24-Ala153
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 95 % as determined by SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at-70 centigrade. Store it under sterile conditions at-20 centigrade to-80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Official Symbol : IL17A
Synonyms : IL17A;interleukin 17A;interleukin-17A

Online Inquiry


  •  
  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved.