Recombinant Rat Ctsd protein, His & GST-tagged
|Product Overview :||Recombinant Rat Ctsd aa. (His120~Leu407 (Accession # P24268)) fused with N-terminal His & GST tag was produced in E. coli cells.|
- Gene Information
- Related Products
|Source :||E. coli|
|Tag :||His & GST|
|Form :||Freeze-dried powder|
|Molecular Mass :||Predicted Molecular Mass: 63.6kDa.|
|Protein length :||His120~Leu407 (Accession # P24268)|
|Endotoxin :||<1.0EU per 1ug (determined by the LAL method)|
|Characteristic :||The isoelectric point is 6.2.|
|Applications :||SDS-PAGE; WB; ELISA; IP.|
|Stability :||The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.|
|Storage :||Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.|
|Storage buffer :||Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.|
|Reconstitution :||Reconstitute in sterile PBS, pH7.2-pH7.4.|
|Gene Name :||Ctsd cathepsin D [ Rattus norvegicus (Norway rat) ]|
|Official Symbol :||Ctsd|
|Synonyms :||cathepsin D|
|Gene ID :||171293|
|mRNA Refseq :||NM_134334.2|
|Protein Refseq :||NP_599161.2|
|UniProt ID :||P24268|
|◆ Recombinant Protein|
|Ctsd-2369M||Recombinant Mouse Ctsd Protein, His-tagged||+Inquiry|
|CTSD-435C||Recombinant Cricetulus Griseus CTSD Protein (65-408 aa), His-SUMO-tagged||+Inquiry|
|CTSD-2103H||Recombinant Human CTSD Protein, GST-tagged||+Inquiry|
|CTSD-877H||Recombinant Human CTSD Protein, His-tagged||+Inquiry|
|CTSD-2752H||Recombinant Human CTSD Protein, His (Fc)-Avi-tagged||+Inquiry|
|◆ Native Protein|
|CTSD-26411TH||Active Native Human Cathepsin D protein||+Inquiry|
|CTSD-27858TH||Native Human CTSD||+Inquiry|
|CTSD-1648H||Active Native Human Cathepsin D||+Inquiry|
|CTSD-3023MCL||Recombinant Mouse CTSD cell lysate||+Inquiry|
|CTSD-1735HCL||Recombinant Human CTSD cell lysate||+Inquiry|
|◆ Assay kits|
|Kit-0264||Cathepsin D Inhibitor Screening Kit||+Inquiry|
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
There is an association between CTSD proteins and cognitive function. In some neurodegenerative diseases, abnormal accumulation and deposition of CTSD proteins may affect neuronal signaling and synaptic function, leading to a decline in cognitive function.
In some neurodegenerative diseases, levels of the CTSD protein may change. For example, people with Alzheimer's disease may have elevated levels of the CTSD protein. These changes may help in the diagnosis of the disease and in the assessment of the course of the disease.
For people with cognitive decline, their CTSD protein levels can be assessed by a blood or cerebrospinal fluid sample. This evaluation can help doctors understand whether the cause of cognitive decline is related to a neurodegenerative disease.
It is currently no treatment that directly targets the CTSD protein. However, some medications can reduce symptoms of neurodegenerative diseases, such as cholinesterase inhibitors such as donepezil, which can increase acetylcholine levels in synapses, which can improve cognitive function.
People with Parkinson's disease may have reduced levels of the CTSD protein. This decrease may be associated with neuronal death and impaired synaptic function. In addition, CTSD protein may also be associated with motor symptoms in patients with Parkinson's disease.
CTSD proteins play a role in Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases. It may change in these diseases, leading to structural alterations and impaired signaling of neuronal synapses.
Customer Reviews (3)Write a review
Good at western-blot experiments. -
In experiments, the biocompatibility performed well. -
The experimental conditions are broad, and the experimental results are accurate and repeatable. -
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