Recombinant Rat Rock2 Protein, His-tagged
Cat.No. : | Rock2-2026R |
Product Overview : | Recombinant Rat Rock2 Protein (Leu904-Gly1140) with N-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
- Download
Description : | Predicted to enable Rho-dependent protein serine/threonine kinase activity. Involved in several processes, including positive regulation of cardiac muscle hypertrophy; positive regulation of connective tissue replacement; and positive regulation of cytokine production. Acts upstream of or within Rho protein signal transduction. Predicted to be located in cytoplasmic ribonucleoprotein granule; cytosol; and spindle pole centrosome. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; centrosome; and glutamatergic synapse. Orthologous to human ROCK2 (Rho associated coiled-coil containing protein kinase 2). |
Source : | E. coli |
Species : | Rat |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 31.0 kDa Accurate Molecular Mass: 31 kDa |
Protein length : | Leu904-Gly1140 |
Purity : | > 90% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | Rock2 Rho-associated coiled-coil containing protein kinase 2 [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Rock2 |
Synonyms : | ROCK2; Rho-associated coiled-coil containing protein kinase 2; rho-associated protein kinase 2; ROKalpha; p164 ROCK-2; p150 ROK-alpha; rhoA-binding kinase 2; Rho-associated coiled-coil forming kinase 2; rho-associated, coiled-coil-containing protein kinase 2; rho-associated, coiled-coil-containing protein kinase II; RhoA - binding serine/threosine kinase alpha (ROK - alpha); ROK; ROCK-II; |
Gene ID : | 25537 |
mRNA Refseq : | NM_013022 |
Protein Refseq : | NP_037154 |
UniProt ID : | Q62868 |
Products Types
◆ Recombinant Protein | ||
ROCK2-1879H | Active Recombinant Human ROCK2 Protein, His-tagged | +Inquiry |
ROCK2-37M | Recombinant Active Mouse ROCK2 Protein (5-554), N-His-tagged | +Inquiry |
ROCK2-3769R | Recombinant Rhesus Macaque ROCK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Rock2-5568M | Recombinant Mouse Rock2 Protein, Myc/DDK-tagged | +Inquiry |
Rock2-2025M | Recombinant Mouse Rock2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ROCK2-2255HCL | Recombinant Human ROCK2 293 Cell Lysate | +Inquiry |
Related Gene
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewSwift and hassle-free delivery ensured our experiments stayed on track.
Efficient customer service provided valuable insights for our decision-making.
Reliable and precise—this recombined protein never disappoints.
Q&As (5)
Ask a questionROCK2 is a key regulator of smooth muscle contraction, influencing vascular tone by phosphorylating myosin light chain and promoting actin-myosin interaction.
ROCK2 interacts with various signaling pathways, including Wnt, PI3K/Akt, and MAPK pathways, forming a network that regulates cell survival, proliferation, and differentiation.
ROCK2 can influence the cell cycle by regulating cyclin-dependent kinase activity and promoting the phosphorylation of proteins involved in cell cycle checkpoints.
ROCK2 is involved in the regulation of cell migration and invasion by controlling actin dynamics and focal adhesion turnover, influencing processes like metastasis in cancer.
ROCK2 phosphorylates various downstream targets, such as myosin light chain, leading to actin-myosin contraction and the reorganization of the actin cytoskeleton.
Ask a Question for All Rock2 Products
Required fields are marked with *
My Review for All Rock2 Products
Required fields are marked with *
Inquiry Basket