Recombinant Sheep TGFA Protein (24-97 aa), GST-tagged

• Cat.No.: TGFA-828S
• Product Overview: Recombinant Sheep TGFA Protein (24-97 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Protein Description: Partial.

Specification

• Description: TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
• Source: E. coli
• Species: Sheep
• Tag: GST
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 34.9 kDa
• Protein length: 24-97 aa
• AA Sequence: ENSTSALSDPPVAAAVVSHFNDCPD SHTQFCFHGTCRFLLQEEKPACVCH SGYVGARCEHADLLAVVAASQKKQ
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.
• UniProt ID: P98135

Gene Information

• UniProt ID: P98135

Reviews

05/03/2020

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04/14/2020

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12/21/2018

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Q&As

How does TGFA contribute to cell growth and proliferation?

It stimulates cell proliferation and survival, playing a key role in tissue development.

How do genetic variations in TGFA affect tissue repair?

Genetic mutations in TGFA can lead to impaired wound healing and tissue regeneration.

What is the impact of altered TGFA activity on cancer development?

Altered TGFA activity is linked with cancer progression, as it can stimulate uncontrolled cell growth.

What is the primary role of TGFA in cell signaling?

TGFA, a growth factor, is vital for activating signaling pathways that control cell growth and differentiation.

What potential therapeutic applications arise from targeting TGFA in regenerative medicine and oncology?

Targeting TGFA offers potential for treating wounds and cancer by modulating growth factor signaling.

How does TGFA interact with other growth factors and receptors?

TGFA interacts with epidermal growth factor receptors, influencing various cellular processes.

What role does TGFA play in wound healing?

TGFA is important in wound healing, promoting the regeneration of skin and other tissues.