btla
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  • Official Full Name
  • B and T lymphocyte associated
  • Background
  • This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.
  • Synonyms
  • BTLA; B and T lymphocyte associated; B- and T-lymphocyte attenuator; BTLA1; CD272; B and T lymphocyte attenuator; B- and T-lymphocyte-associated protein; FLJ16065; MGC129743
Cat.#:BTLA-348HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTLA Protein (Lys 31 - Ser 150), His-tagged
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Cat.#:BTLA-567HTag:Fc-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTLA Protein, Fc-Avi-tagged, Biotinylated
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Cat.#:BTLA-568HTag:His-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTLA Protein, His-Avi-tagged, Biotinylated
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Cat.#:BTLA-2828HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTLA Protein, MYC/DDK-tagged
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Cat.#:BTLA-3037HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human B and T Lymphocyte Associated, His-tagged
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Cat.#:BTLA-017HTag:DDK/His
Source (Host):Human 293HEK cellsSpecies:Human
Product nameRecombinant Human BTLA protein, DDK/HIS-tagged
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Cat.#:BTLA-018HTag:DDK/His
Source (Host):Human 293HEK cellsSpecies:Human
Product nameRecombinant Human BTLA protein, DDK/HIS-tagged
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Cat.#:BTLA-188HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human BTLA, MIgG2a Fc-tagged
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Cat.#:BTLA-189HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human BTLA, HIgG1 Fc-tagged
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Cat.#:BTLA-190HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTLA protein, His-tagged
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Cat.#:BTLA-191HTag:Fc/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTLA protein, Fc/His-tagged
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Cat.#:BTLA-192HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTLA, Fc-tagged
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Cat.#:BTLA-233HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTLA protein, Fc-tagged
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Cat.#:BTLA-27110THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BTLA, His-tagged
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Cat.#:BTLA-389HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BTLA Protein, GST-tagged
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Cat.#:BTLA-411HTag:Fc Chimera
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human BTLA, Fc Chimera
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Cat.#:BTLA-565HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human BTLA, Fc-tagged, Biotinylated
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Cat.#:BTLA-566HTag:Fc/Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTLA Protein, Fc & Avi-tagged, Biotinylated
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Cat.#:Btla-1843MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Btla protein, His & T7-tagged
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Cat.#:BTLA-8698MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse BTLA, Fc tagged
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Cat.#:BTLA-8699MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse BTLA Protein, His-tagged
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Cat.#:BTLA-1032RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat BTLA Protein
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Cat.#:BTLA-1148RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat BTLA Protein, Fc-tagged
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Cat.#:Btla-1844RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Btla protein, His & T7-tagged
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Cat.#:BTLA-195CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus BTLA, Fc-tagged
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Cat.#:BTLA-1525RTag:hIgG1
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey BTLA Protein, hIgG1-tagged
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Cat.#:BTLA-1526RTag:hIgG4
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey BTLA Protein, hIgG4-tagged
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Cat.#:BTLA-1278MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse BTLA cell lysate
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Cat.#:BTLA-732CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus BTLA cell lysate
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Involved Pathway

BTLA involved in several pathways and played different roles in them. We selected most pathways BTLA participated on our site, such as Adaptive Immune System, Costimulation by the CD28 family, Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with BTLA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
CD300A; VPRBP; IGHM; KIF3B; TRAF7; NA; CLEC2D; ASB4; ASB6; FRS2A
Costimulation by the CD28 family
PDPK1A; CTLA4; MAPKAP1; MAP3K8; BTLA; CSK; THEM4; HLA-DQB2
Immune System
HUWE1; CD300LD; CXADR; Txn1; CTSO; LILRB2; IFIT12; LILRB4; TRIM69; AF251705

Protein Function

BTLA has several biochemical functions, for example, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BTLA itself. We selected most functions BTLA had, and list some proteins which have the same functions with BTLA. You can find most of the proteins on our site.
Function
Related Protein
Function receptor activity
Related Protein GRIN1B; NLGN2; P2RY2; NR2C2; KLRB1F; CALCR; NLGN3A; OGFRL1; TLR4; GRIA3B

Interacting Protein

BTLA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BTLA here. Most of them are supplied by our site. Hope this information will be useful for your research of BTLA.
TNFRSF14; PTPN6; PTPN11

BTLA Related Articles

Venner, JM; Famulski, KS; et al. Molecular Landscape of T Cell-Mediated Rejection in Human Kidney Transplants: Prominence of CTLA4 and PD Ligands. AMERICAN JOURNAL OF TRANSPLANTATION 14:2565-2576(2014).
Uchiyama, M; Jin, X; et al. Combination of Anti-BTLA Antibody (6B2) and Anti-PD-1 Antibody (PIM-2) Induced Indefinite Survival of Fully MHC-Mismatched Murine Cardiac Allograft.. TRANSPLANTATION 98:311-311(2014).

BTLA Related Gene Family

Immunoglobulins