CD200
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Official Full Name
CD200 antigen
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Overview
CD200, known as OX-2, is a type I membrane glycoprotein member of the Ig supergene family. CD200 is expressed on B cells, a subset of T cells, thymocytes, follicular dendritic cells, neurons, keratinocytes, vascular endothelium, and some smooth muscle. Th -
Synonyms
CD200; CD200 antigen; OX-2 membrane glycoprotein; MRC OX-2 antigen; antigen identified by monoclonal MRC OX-2; OX2; Mox2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Cynomolgus Monkey
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Rhesus
- Rhesus Macaque
- CHO
- E.coli
- E.coli expression system
- HEK293
- HEK293 cells
- HEK293F
- HEK293T
- Human Cell
- Human cells
- Human Cells
- Human Expi293 cells
- In Vitro Cell Free System
- Insect Cell
- Insect cells
- Mammalian Cell
- Mammalian cells
- NS0
- Wheat Germ
- C
- 6×His
- His
- Myc
- DDK
- DYKDDDDK
- Fc
- Avi
- Fc|His
- GST
- hFc
- His (Fc)
- human|IgG1|Fc
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- CD200 Related Articles
- CD200 Related Research Area
CD200 involved in several pathways and played different roles in them. We selected most pathways CD200 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD200 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Adaptive Immune System | LILRA3;TRAT1;B2ML;TRIM50;SIGLEC7;PIK3AP1;CTS7;UBE2L6;BTLA |
Immune System | HERC5;RNF25;PELI3;DEFB1;ARIH1;BTR02;TREML4;MICA;KIF20A |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | CD300E;CD300LD;LAIR1;LILRA3;KIR2DS2;SIGLEC10;TREM1;KLRG1;SIGLEC8 |
CD200 has several biochemical functions, for example, cell adhesion molecule binding, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CD200 itself. We selected most functions CD200 had, and list some proteins which have the same functions with CD200. You can find most of the proteins on our site.
Function | Related Protein |
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cell adhesion molecule binding | JUP;NLGN2;SDCBP;DSP;NRXN1;SELL;CADM2;LILRB2;NRXN2 |
protein binding | CEP350;KIF9;XRN1;SERPINF1;AUNIP;GTF2A2;CHMP4C;FLOT2;MYO6 |
protein homodimerization activity | TFAP2A;ANXA9;AMICA1;CTSE;KCNK9;UGT1A6B;TIMELESS;DPP4;ABCD3 |
receptor activity | NLGN3A;CADM1B;ANPEP;CNTNAP1;TREM2;MED12;RET;NLGN4B;PLXNA1 |
receptor binding | MBL2;PLAUR;ABL2;WNT7AA;ADM;FGF10B;EFNA1;LAMA1;LTB |
CD200 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD200 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD200.
CD200R1; HUS1
- Q&As
- Reviews
Q&As (7)
Ask a questionCD200 regulates bone marrow and hematopoietic environments, supporting stem cell maintenance and differentiation.
CD200 contributes to immune evasion in cancers, affecting tumor progression and response to immunotherapy.
CD200 plays a role in suppressing inflammatory responses, which is crucial in autoimmune disease management.
Dysregulation of CD200 affects tissue graft rejection, influencing transplant tolerance and success.
Changes in CD200 expression impact the aging immune system, affecting age-related immune regulation and function.
CD200 expression influences neuroinflammatory processes, potentially impacting neurodegenerative diseases.
CD200 interacts with CD200R to modulate immune responses, promoting immune tolerance and reducing inflammation.
Customer Reviews (3)
Write a reviewSwift protein sequencing, helps identify unknown proteins.
Great protein crystallization services, key for structural biology.
Invaluable protein-protein interaction assays, integral for research.
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