il1r1
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  • Official Full Name
  • interleukin 1 receptor, type I
  • Background
  • Tumor Necrosis Factor Receptor Type I (TNFRI); is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-alpha and TNF-beta; (also known as LT-alpha );. The subsequen
  • Synonyms
  • IL1R1; interleukin 1 receptor, type I; IL1R, IL1RA; interleukin-1 receptor type 1; CD121A; D2S1473; IL-1R-1; IL-1RT1; IL-1RT-1; antigen CD121a; interleukin receptor 1; interleukin-1 receptor alpha; interleukin-1 receptor type I; CD121 antigen-like family
Cat.#:IL1R1-14174HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL1R1, His-tagged
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Cat.#:IL1R1-214HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL1R1 Protein
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Cat.#:IL1R1-251HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human IL1R1
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Cat.#:IL1R1-299HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL1R1, Fc-tagged
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Cat.#:IL1R1-3011HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human IL1R1, MIgG2a Fc-tagged
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Cat.#:IL1R1-3012HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human IL1R1, HIgG1 Fc-tagged
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Cat.#:IL1R1-368HTag:His
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human IL1R1 Protein, His-tagged
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Cat.#:IL1R1-527HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL1R1, DDDDK tagged
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Cat.#:IL1R1-552HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL1R1 protein, His-tagged
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Cat.#:IL1R1-627HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human IL1R1, Fc-tagged, Biotinylated
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Cat.#:IL1R1-771HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL1R1, Fc tagged
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Cat.#:IL1R1-772HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL1R1, His tagged
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Cat.#:IL1R1-879HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL1R1 protein, His-tagged
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Cat.#:Il1r1-5188MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Il1r1, His tagged
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Cat.#:Il1r1-5651MTag:Fc
Source (Host):S. frugiperdaSpecies:Mouse
Product nameRecombinant Mouse Interleukin 1 Receptor, Type I, Fc-tagged
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Cat.#:Il1r1-5652MTag:His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Interleukin 1 Receptor, Type I, His-tagged
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Cat.#:Il1r1-5653MTag:Fc
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Interleukin 1 Receptor, Type I, Fc-tagged
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Cat.#:Il1r1-881MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il1r1 protein, His & T7-tagged
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Cat.#:IL1R1-917MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse IL1R1 Protein, Fc-tagged
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Cat.#:Il1r1-4088RTag:FC/His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Il1r1, Fc-His tagged
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Cat.#:Il1r1-4089RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Il1r1, His tagged
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Cat.#:Il1r1-882RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Il1r1 protein, His-tagged
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Cat.#:Il1r1-883RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Il1r1 protein, His-tagged
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Cat.#:Il1r1-884RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Il1r1 protein, His-tagged
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Cat.#:IL1R1-148CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IL1R1, Fc tagged
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Cat.#:IL1R1-149CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IL1R1, His tagged
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Cat.#:IL1R1-7034CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken IL1R1
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Cat.#:IL1R1-1640HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Interleukin 1 Receptor, Type I
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Cat.#:IL1R1-286HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interleukin 1 Receptor, Type I, His-tagged
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Cat.#:Il1r1-1753MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Interleukin 1 Receptor, Type I
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Cat.#:IL1R1-1120HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL1R1 cell lysate
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Cat.#:IL1R1-1787MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse IL1R1 cell lysate
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Cat.#:IL1R1-1935RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat IL1R1 cell lysate
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Cat.#:IL1R1-945CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IL1R1 cell lysate
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Cat.#:IL1R1&IL1RAcP-P01HTag:Fc
Source (Host):Species:Human
Product nameRecombinant Human IL1R1/IL1RAcP, Fc-tagged therapeutic protein
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Involved Pathway

IL1R1 involved in several pathways and played different roles in them. We selected most pathways IL1R1 participated on our site, such as MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL1R1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
PPM1A; MAPK4; MAPK13; MEF2C; RELB; MAPK14A; HSPA1L; RAP1B; ARRB2; RAC3B
Cytokine-cytokine receptor interaction
GH1; IL7R; CXCR3.1; CXCL14; CCL20; IL8L2; Cxcl15; Pdgfa&Pdgfb; CCL20A.3; TNFRSF11B
NF-kappa B signaling pathway
Bcl2a1b; TRAF2; PIAS4; PLCG2; TNFSF11; CCL21B; RELB; TNFRSF1A; CCL4; TAB2
Apoptosis
TRADD; IRAK3; DFFB; AKT1; IRAK4; BIRC3; TNFRSF10A; TNFSF10; BOKA; HMGB2
Osteoclast differentiation
TREM2; TRAF6; FOSL2; NFKB1; SFPI1; AKT2; MAP3K14; SIRP-BETA; LILRB4; RAC1
Hematopoietic cell lineage
KITLG; ANPEP; CD9; CD59; CD1D; GM2002; CD8A; HLA-DRB1; CD44; ITGAM
Inflammatory mediator regulation of TRP channels
CYP2C39; PLA2G4C; HTR2A; MAPK11; PPP1CA; CYP2C37; CYP2J2; PLCB1; MAPK13; CYP2C70
Amoebiasis
COL5A1; SERPINB1; CD1D; CD1d1; TGFB1; CSF2; COL1A1; PLCB1; VCL; GM-CSF
HTLV-I infection
BUB3; HLA-DQA2; FZD7; PPP3CA; CCNB2; FZD9; XIAP; IL15; IL2RB; TSPO

Protein Function

IL1R1 has several biochemical functions, for example, interleukin-1 receptor activity, interleukin-1, Type I, activating receptor activity, ionotropic glutamate receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL1R1 itself. We selected most functions IL1R1 had, and list some proteins which have the same functions with IL1R1. You can find most of the proteins on our site.
Function
Related Protein
Function interleukin-1 receptor activity
Related Protein IL1R1; IL1RAPL1A; IL1RL2; IL1R2; IL1RAP; IL1RAPL2; IL1RL1; IL18R1
Function interleukin-1, Type I, activating receptor activity
Related Protein IL1R1; IL1RL2
Function ionotropic glutamate receptor binding
Related Protein DLG4B; CACNG2; DLG3; RAB4A; SHANK2; NETO1; SHANK1; DLG4; FUS; DLG2
Function platelet-derived growth factor receptor binding
Related Protein FIGF; PDGFRA; ITGA5; VEGFA; PTEN; PDGFRB; PTPRJ; PDGFC; PDGFAB; PDGFAA
Function protease binding
Related Protein TYSND1; CSTA; OS9; ELANE; ECM1; BCL2; ADAMTS4; TNF; XBP1; Serpina1c
Function protein binding
Related Protein RBM15; KIR2DL1; CALCA; PNMA2; LAIR2; CRABP1; MAP1S; KRTAP19-5; TOR1A; C1orf38
Function signal transducer activity
Related Protein CRKL; ADORA2AB; STAT2; S1PR5A; GNAO1; YARS; CD40; GNG12A; APOL3; GNG3
Function transmembrane signaling receptor activity
Related Protein CD97; OR115-6; TNFRSF11A; EGFR; NPC1; CLEC2H; P2RX6; KLRB1; FZD8B; NRXN3

Interacting Protein

IL1R1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL1R1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL1R1.
TRAF6; IL1B; IL1RN; TICAM2; IL1RAP; MAP3K14

IL1R1 Related Articles

Suwara, MI; Green, NJ; et al. IL-1 alpha released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts. MUCOSAL IMMUNOLOGY 7:684-693(2014).
Britze, A; Palmfeldt, J; et al. 44-plex cytokine profile of cholesteatoma. ACTA OTO-LARYNGOLOGICA 134:41-50(2014).

IL1R1 Related Gene Family

IL