|Official Full Name||oncostatin M|
|Background||Oncostatin M, also known as OSM, is a protein that in humans is encoded by the OSM gene. OSM is a pleiotropic cytokine that belongs to the interleukin 6 group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. However, it is as yet poorly defined and is proving important in liver development, haematopoeisis, inflammation and possibly CNS development. It is also associated with bone formation and destruction.|
|Synonyms||OSM; oncostatin M; MGC20461; oncostatin-M; OTTHUMP00000198700|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
OSM involved in several pathways and played different roles in them. We selected most pathways OSM participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with OSM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cytokine-cytokine receptor interaction||IL-15RA; TNFRSF8; TGFB1A; CCL13; CCR6; IL8L2; FIGF; Il2; GM13305; IFNA21|
|PIK-Akt signaling pathway||RHEB; ITGA5; GNG4; PPP2CB; GNB2; FLT4; PPP2R5B; CREB3L3; BCL2L1; GNG7|
|Jak-STAT signaling pathway||BCL2A; IL4R; Il6ra; PIK3R2; GM-CSF; AOX2P; MCL1; LEPA; IFNA8; IFNA3|
OSM has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by OSM itself. We selected most functions OSM had, and list some proteins which have the same functions with OSM. You can find most of the proteins on our site.
|cytokine activity||LIF; VSTM1; GM13288; INHBC; CMTM4; INHBAA; IL36B; OSTN; IL9; THPO|
|growth factor activity||FGF13; GDF2; CSF1; COL20A1; KLK1B4; FGF12; GDNFA; MDKB; PDGFB; OGN|
|oncostatin-M receptor binding||OSM|
OSM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OSM here. Most of them are supplied by our site. Hope this information will be useful for your research of OSM.
IL6ST; LIFR; COL4A6; TNNT1