"MGMT" Related Products

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Recombinant Human O-6-methylguanine-DNA Methyltransferase, T7-tagged

Cat. No. : MGMT-814H
Product Overview : Recombinant MGMT protein, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques, 21646Da (207aa).
Description : Methylated-DNA-protein-cysteine methyltransferase is an enzyme that in humans is encoded by the MGMT gene.
Sequences of amino acids : MDKDCEMKRT TLDSPLGKLE LSGCEQGLHE IKLLGKGTSA ADAVEVPAPA AVLGGPEPLM QCTAWLNAYF HQPEAIEEEP VPALHHPVFQ QESFTRQVLW KLLKVVKFGE VISYQQLAAL AGNPKAARAV GGAMRGNPVP ILIPCHRVVC SSGAVGNYSG GLAVKEWLLA HEGHRLGKPG LGGSSGLAGA WLKGAGATSG SPPAGRN
Formulation : 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3
Purity : > 95% by SDS - PAGE
Applications : MS. SDS
Gene Name : MGMT O-6-methylguanine-DNA methyltransferase [Homo sapiens]
Synonyms : MGMT; O-6-methylguanine-DNA methyltransferase; methylated-DNA-protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase; methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase; EC2.1.1.63; O6-methylguanine-DNA methyltransferase
Gene ID : 4255
mRNA Refseq : NM_002412
Protein Refseq : NP_002403
MIM : 156569
UniProt ID : P16455
Chromosome Location : 10q26
Pathway : Reactome Event: DNA Repair
Function : DNA binding; DNA-methyltransferase activity; metal ion binding; methylated-DNA-[protein]-cystein S-methyltransferase activity; methyltransferase activity; transferase activity

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