"MGMT" Related Products

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Recombinant Human O-6-methylguanine-DNA Methyltransferase, T7-tagged

Cat. No.: MGMT-814H
Product Overview: Recombinant MGMT protein, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques, 21646Da (207aa).
Description: Methylated-DNA-protein-cysteine methyltransferase is an enzyme that in humans is encoded by the MGMT gene.
Sequences of amino acids: MDKDCEMKRT TLDSPLGKLE LSGCEQGLHE IKLLGKGTSA ADAVEVPAPA AVLGGPEPLM QCTAWLNAYF HQPEAIEEEP VPALHHPVFQ QESFTRQVLW KLLKVVKFGE VISYQQLAAL AGNPKAARAV GGAMRGNPVP ILIPCHRVVC SSGAVGNYSG GLAVKEWLLA HEGHRLGKPG LGGSSGLAGA WLKGAGATSG SPPAGRN
Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3
Purity: > 95% by SDS - PAGE
Applications: MS. SDS
Gene Name: MGMT O-6-methylguanine-DNA methyltransferase [Homo sapiens]
Synonyms: MGMT; O-6-methylguanine-DNA methyltransferase; methylated-DNA-protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase; methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase; EC2.1.1.63; O6-methylguanine-DNA methyltransferase
Gene ID: 4255
mRNA Refseq: NM_002412
Protein Refseq: NP_002403
MIM: 156569
UniProt ID: P16455
Chromosome Location: 10q26
Pathway: Reactome Event: DNA Repair
Function: DNA binding; DNA-methyltransferase activity; metal ion binding; methylated-DNA-[protein]-cystein S-methyltransferase activity; methyltransferase activity; transferase activity

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