Native Rat Alpha-2-Macroglobulin

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Native Rat Alpha-2-Macroglobulin

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Cat. No. : A2m-695R
Product Overview : Native Rat A2m isprepared from Rat serum.
Description : Nativerat A2m is a large plasma protein found in the blood. A2m is produced by theliver and is a major component of the alpha-2 band in proteinelectrophoresis.
Form : Liquid in 10 mMsodium phosphate buffer, pH 7.2, +10 mM NaCl.
Source : Rat serum
Purity : > 96% asdetermined by SDS-PAGE analysis
Concentration : > 0.5 mg/ml
Molecular Weight : 175 kDa
Endotoxin Level : 0.1 ng/ug of protein
Storage : Store at -80°C.Stable for 1 year. Avoid repeated freeze-thaw cycles.
Pathways : Complement and Coagulation Cascades;Formation of Fibrin Clot (Clotting Cascade); Hemostasis; Intrinsic Pathway;Platelet activation; Platelet degranulation; Rho GTPase cycle; SignalTransduction; Signaling by Rho GTPases
Crystal structure of alpha-2-macroglobulin. Rendered from PDB2P9R. :

Gene Name : A2malpha-2-macroglobulin [ Rattus norvegicus ]
Official Symbol : A2m
Synonyms : A2m;alpha-2-macroglobulin; Mam; A2m1; A2maa; A2MAC1; MGC114358;RATA2MAC1; alpha-2-macroglobulin; alpha-2-M; alpha-2-macroglobulin-P
Gene ID : 24153
mRNA Refseq : NM_012488
Protein Refseq : NP_036620
MIM : P06238
Chromosome Location : 4
Function : endopeptidaseinhibitor activity; enzyme binding; growth factor binding; interleukin-1binding; interleukin-8 binding; peptidase inhibitor activity; receptorbinding; serine-type endopeptidase inhibitor activity; tumor necrosis factorbinding

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