Active Recombinant Mouse Interleukin 23 Receptor, Fc-tagged
Cat.No. : | Il23r-5657M |
Product Overview : | RecombinantMouse Il23r protein was expressed in Murine myeloma celllinewith the Fc part of Human IgG1 Pro100-Lys330 (C-terminus) and MouseIl23r Gly24-Asp372 (N-terminus). |
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Cat. No. : | Il23r-5657M |
Description : | Il23r isa heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunitthat is unique to IL-23, and a p40 subunit that is shared with IL-12. Thefunctional Il23r complex consists of two receptor subunits, the IL-12receptor beta 1 subunit (IL-12 Rβ1) and the IL-23-specific receptor subunit(IL-23 R). Mouse Il23r cDNA encodes a 644 amino acid (aa) type I transmembraneprotein with a 23 aa residue signal peptide, a 349 aa residue extracellulardomain, a 23 aa residue transmembrane domain and a 249 aa residue cytoplasmicregion. |
Source : | Mammalian cells |
Form : | Lyophilizedfrom a 0.2 μm filtered solution in PBS. |
N-terminalSequence : | Gly24 |
MolecularWeight : | 66.8 kDa (monomer) |
Activity : | Measuredby its binding ability in a functional ELISA. Immobilized rm Il23r/FcChimera at 5 μg/mL (100 μL/well) can bind rmIL-23 with a linear range of 0.6-40ng/mL. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 105 kDa,reducing conditions. |
Purity : | >90%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | 100 μg/mLin sterile PBS |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to-70°C under sterile conditions after reconstitution. |
Gene Name : | Il23r interleukin 23 receptor[ Mus musculus ] |
Official Symbol : | Il23r |
Synonyms : | Il23r; interleukin23 receptor; IL-23R; interleukin-23receptor; IL-23 receptor |
Gene ID : | 209590 |
mRNA Refseq : | NM_144548 |
Protein Refseq : | NP_653131 |
UniProt ID : | Q8K4B4 |
Chromosome Location : | 6 |
Pathway : | Cytokine-cytokinereceptor interaction; Jak-STAT signaling pathway |
Function : | interleukin-23binding; interleukin-23 receptor activity; receptor activity |
Products Types
◆ Recombinant Protein | ||
Il23r-71M | Recombinant Mouse Il23r Protein, His (Fc)-Avi-tagged | +Inquiry |
Il23r-8801R | Active Recombinant Rat Il23r protein(Met1-Asp367), hFc-tagged | +Inquiry |
Il23r-327M | Recombinant Mouse Il23r Protein, Fc-tagged | +Inquiry |
Il23r-1030R | Recombinant Rat Il23r Protein, His-tagged | +Inquiry |
IL23R-1110R | Recombinant Rat IL23R Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IL23R-1429CCL | Recombinant Cynomolgus IL23R cell lysate | +Inquiry |
IL23R-1213HCL | Recombinant Human IL23R cell lysate | +Inquiry |
IL23R-1234RCL | Recombinant Rat IL23R cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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