Recombinant Mouse Interleukin 28a

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Recombinant Mouse Interleukin 28a

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Cat. No. : Il28a-229M
Description : Interleukin-28A (IL-28A) also known as IFNL2 is a novel cytokine that exerts its biological effects through a receptor that also binds IL28B and IL29. IL28A induces phosphorylation of STAT1, STAT2, and STAT3 IL-28A has antiviral activities and stimulates antiviral responses through a heterodimeric receptor. IL-28A represents a potential novel approach for therapy of Th1-mediated inflammatory diseases such as T-cell-mediated hepatitis.
Source : NSO Cells.
Molecular Weight : The predicted molecular weight of Recombinant Mouse IL-28A is Mr 20.5 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 25-30 kDa.
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : Il28a interleukin 28A [ Mus musculus ]
Synonyms : Il28a; interleukin 28A; Ifnl2; EG330496; IFN-lambda2; interferon-lambda2
Gene ID : 330496
mRNA Refseq : NM_001024673
Protein Refseq : NP_001019844
UniProt ID : Q4VK74
Chromosome Location : 7
Pathway : Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function : cytokine activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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