"CDK7/CCNH" Related Products

Recombinant Human CDK7/CCNH Active protein, His-tagged

Cat.No.: CDK7-CCNH-313H
Product Overview: Recombinant full-length human CDK7 and CCNH were co-expressed by baculovirus in Sf9 insect cells using an N-terminal His tags.
Description: CDK7 gene is a member of the cyclin-dependent protein kinase family that is important regulators of cell cycle progression. CDK7 forms a trimeric complex with cyclin H and MAT1, which functions as a CDK-activating kinase (CAK). CDK7 is an essential component of the transcription factor TFIIH that is involved in transcription initiation and DNA repair. CDK7 is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Source: Insect cell
Species: Human
Tag : His
Form: 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol
Bio-activity: The specific activity of CDK7/CyclinH1 was determined to be 56nmol/min/mg as per activity protocol.
Molecular Mass: CDK7 ~41~43 kDa, and CCNH ~39 kDa
Purity: The purity of CDK7/CCNH was determined to be >70% by densitometry.
Applications: Kinase Assay; WB
Stability: 1 year at -70 centigrade
Storage: Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration: 0.1 μg/μL
Gene Name: cyclin dependent kinase 7 [ Homo sapiens (human) ]; cyclin H [ Homo sapiens (human) ]
Official Symbol: CDK7; CCNH
Synonyms: CAK; CAK1; HCAK; MO15; STK1; CDKN7; P39mo15; Cyclin H1; CCNH; CAK; p34; p37
Gene ID: 1022; 902
mRNA Refseq: NM_001799; NM_001239
Protein Refseq: NP_001790.1; NP_001230.1
MIM: 601955; 601953
UniProt ID: P50613; P51946

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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