Recombinant Human FGF23 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : FGF23-3431H
Product Overview : FGF23 MS Standard C13 and N15-labeled recombinant protein (NP_065689) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 28 kDa
AA Sequence : MLGARLRLWVCALCSVCSMSVLRAY PNASPLLGSSWGGLIHLYTATARNS YHLQIHKNGHVDGAPHQTIYSALMI RSEDAGFVVITGVMSRRYLCMDFRG NIFGSHYFDPENCRFQHQTLENGYD VYHSPQYHFLVSLGRAKRAFLPGMN PPPYSQFLSRRNEIPLIHFNTPIPR RHTRSAEDDSERDPLNVLKPRARMT PAPASCSQELPSAEDNSPMASDPLG VVRGGRVNTHAGGTGPEGCRPFAKF ITRTRPLEQKLISEEDLAANDILDY KDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : FGF23 fibroblast growth factor 23 [ Homo sapiens (human) ]
Official Symbol : FGF23
Synonyms : FGF23; fibroblast growth factor 23; ADHR; FGFN; HYPF; HFTC2; HPDR2; PHPTC; fibroblast growth factor 23; phosphatonin; tumor-derived hypophosphatemia inducing factor
Gene ID : 8074
mRNA Refseq : NM_020638
Protein Refseq : NP_065689
MIM : 605380
UniProt ID : Q9GZV9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (7)

Ask a question
What role does FGF23 play in chronic kidney disease? 06/12/2022

FGF23 levels are elevated in chronic kidney disease, contributing to mineral imbalance.

How is FGF23 implicated in cardiovascular health? 04/04/2022

High FGF23 levels are associated with increased cardiovascular risk.

How does FGF23 regulate phosphate and calcium homeostasis? 03/24/2022

It decreases renal phosphate reabsorption and 1,25-dihydroxyvitamin D production.

Are there known genetic mutations that affect FGF23 production or activity? 01/27/2022

Mutations in FGF23 or related proteins can lead to dysregulated phosphate metabolism.

What therapeutic strategies are being explored to modulate FGF23 levels? 05/16/2020

Strategies include phosphate binders and FGF23 antibodies to manage elevated FGF23 levels.

In which tissues is FGF23 predominantly produced and secreted? 04/28/2020

FGF23 is primarily produced in bone.

What is the primary function of FGF23 in the body? 10/29/2019

FGF23 regulates phosphate and vitamin D metabolism.

Customer Reviews (3)

Write a review
Reviews
07/23/2022

    Excellent results, high purity. -

    07/17/2021

      Reliable and effective product. -

      11/26/2020

        Quick delivery, product works. -

        Ask a Question for All FGF23 Products

        Required fields are marked with *

        My Review for All FGF23 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        Stay Updated on the
        Latest Bioscience Trends

        Copyright © 2023 Creative BioMart. All Rights Reserved.

        Terms and Conditions        Privacy Policy