Active Recombinant Mouse Cfh Protein, His-tagged
Cat.No. : | Cfh-626M |
Product Overview : | Recombinant Mouse Cfh (Accession # NP_034018) Ser875-Val1252, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian cells |
Species : | Mouse |
Tag : | His |
Predicted N Terminal : | Ser875 |
Form : | Lyophilized from a 0.2 µm filtered solution in Tris and NaCl. |
Bio-activity : | Measured by the ability of the immobilized protein to induce the adhesion of human neutrophils. DiScipio, R.G. et al. (1998) J. Immunol. 160:4057.The ED50 for this effect is typically 3 - 18 µg/mL in the presence of 50 ng/mL of rhTNF-alpha. |
Molecular Mass : | Recombinant Mouse Cfh, His-tagged has a calculated MW of 43.2 kDa. In SDS-PAGE migrates as 64 kDa, reducing conditions. |
Protein length : | Ser875-Val1252 |
Purity : | >90%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Reconstitution : | Reconstitute at 10 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Gene Name : | Cfh complement component factor h [ Mus musculus ] |
Official Symbol : | Cfh |
Synonyms : | CFH; complement component factor h; complement factor H; protein beta-1-H; complement factor H related protein 3A4/5G4; NOM; Sas1; Mud-1; Sas-1; |
Gene ID : | 12628 |
mRNA Refseq : | NM_009888 |
Protein Refseq : | NP_034018 |
MIM : |
Products Types
◆ Recombinant Protein | ||
CFH-762H | Recombinant Human CFH Protein, His-tagged | +Inquiry |
Cfh-761M | Recombinant Mouse Cfh Protein, His-tagged | +Inquiry |
CFH-1168H | Recombinant Human CFH Protein, GST-Tagged | +Inquiry |
CFH-763H | Recombinant Human CFH Protein, His-tagged | +Inquiry |
Cfh-1612M | Recombinant Mouse Cfh Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
CFH-115H | Active Native Human Factor H | +Inquiry |
CFH-23H | Active Native Human Complement factor H | +Inquiry |
◆ Lysates | ||
CFH-2409HCL | Recombinant Human CFH cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMutations in CFH increase the risk of aHUS, affecting complement regulation and leading to kidney damage.
CFH controls the complement system, preventing its overactivation and protecting against immune damage.
CFH modulates the immune response to bacterial infections, balancing defense mechanisms.
CFH deficiency is linked to AMD, due to impaired regulation of the complement pathway in the retina.
CFH shields host cells from complement-mediated injury, maintaining tissue integrity.
CFH regulates inflammation and maintains immune balance, crucial for preventing excessive immune responses.
Changes in CFH function can impact kidney health, potentially leading to renal diseases due to altered complement activity.
Customer Reviews (3)
Write a reviewExceptional protein expression optimization support, highly appreciated assistance.
Precise protein quantification, ensures data accuracy in our research.
Timely antibody validation, an invaluable asset for our laboratory.
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