Recombinant Rat IL25 Protein IL25-5209R

Recombinant Rat IL25 Protein

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Cat.No. : IL25-5209R Optional Service: Optional requirements on this protein
Product Overview : Rat IL25 recombinant protein expressed in Escherichia coli.
Description : The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. This cytokine can induce NF-kappaB activation, and stimulate the production of IL8. Both this cytokine and IL17B are ligands for the cytokine receptor IL17BR. Studies of the similar gene in mice suggested that this cytokine may be a proinflammatory cytokine favoring Th2-type immune response. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Source : E. coli
Species : Rat
Form : Lyophilized
Bio-activity : The activity is determined by the dose-dependent induction of human IL-8 production from human PBMCs. The expected ED50 for this effect is 25-37.5 ng/mL.
Molecular Mass : 35.5 kDa
AA Sequence : MCSHLPRCCP SKQQEFPEEW LKWNPAPVSP PEPLRHTHHP ESCRASKDGP LNSRAISPWS YELDRDLNRV PQDLYHARCL CPHCVSLQTG SHMDPMGNSV PLYHNQTVFY RRPCHGEQGA HGRYCLERRL YRVSLACVCV RPRMMA
Endotoxin : < 0.1 EU/μg
Applications : Functional Study
SDS-PAGE
Storage : Store at -20 centigrade on dry atmosphere. After reconstitution with sterilized 20 mM HCl, store at -20 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : No additive
Quality Control Testing :

1 μg/lane in 4-20% Tris-Glycine gel stained with Coomassie Blue
Lane 1: non-reducing conditions
Lane 2: reducing conditions

Gene Name : Il25 interleukin 25 [ Rattus norvegicus ]
Official Symbol : IL25
Synonyms : IL25; interleukin 25; interleukin-25; RGD1561632;
Gene ID : 501996
mRNA Refseq : NM_001192007
Protein Refseq : NP_001178936
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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