adipoq
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  • Official Full Name
  • adiponectin, C1Q and collagen domain containing
  • Background
  • Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
  • Synonyms
  • ADIPOQ; adiponectin, C1Q and collagen domain containing; APN; Acdc; apM1; 30kDa; GBP28; adipo; Acrp30; adiponectin; adipocyte-specific protein AdipoQ; adipocyte complement related protein; 30 kDa adipocyte complement-related protein; adipocyte complement-related 30 kDa protein; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein;
Cat.#:ADIPOQ-1061HTag:His
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human Adiponectin Protein
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Cat.#:ADIPOQ-1376HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADIPOQ Protein, MYC/DDK-tagged
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Cat.#:ADIPOQ-1362MTag:His
Source (Host):Insect cellsSpecies:Mouse
Product nameRecombinant Mouse ADIPOQ Protein, His-tagged
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Cat.#:Adipoq-5373MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Adiponectin, C1Q And Collagen Domain Containing
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Cat.#:Adipoq-5443RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Adiponectin, C1Q And Collagen Domain Containing
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Cat.#:ADIPOQ-169HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Adiponectin, C1Q And Collagen Domain Containing
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Cat.#:ADIPOQ-1849HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Adiponectin, C1Q And Collagen Domain Containing
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Cat.#:ADIPOQ-45HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADIPOQ, Flag-tagged
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Cat.#:ADIPOQ-47HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADIPOQ, Trimeric Form
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Cat.#:Adipoq-117MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Adipoq, Globular Domain, His-tagged
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Cat.#:Adipoq-118MTag:Flag
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Adipoq (Trimer), Flag-tagged
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Cat.#:Adipoq-47MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Adiponectin, C1Q and Collagen Domain Containing, His-tagged
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Cat.#:Adipoq-48MTag:N/A
Source (Host):HEK293Species:Mouse
Product nameadiponectin, C1Q and collagen domain containing
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Cat.#:ADIPOQ-188DTag:Flag
Source (Host):HEK293Species:Dog
Product nameRecombinant Dog ADIPOQ, FLAG-tagged
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Cat.#:ADIPOQ-189DTag:Flag
Source (Host):HEK293Species:Dog
Product nameRecombinant Dog ADIPOQ, Globular Domain, FLAG-tagged
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Cat.#:ADIPOQ-209HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOQ, His-tagged
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Cat.#:ADIPOQ-210HTag:HIS
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOQ, His-tagged
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Cat.#:ADIPOQ-211HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADIPOQ
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Cat.#:Adipoq-216MTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Adipoq
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Cat.#:ADIPOQ-218PTag:Flag
Source (Host):HEK293Species:Porcine
Product nameRecombinant Porcine ADIPOQ, Flag-tagged
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Cat.#:ADIPOQ-267PTag:Flag
Source (Host):HEK293Species:Porcine
Product nameRecombinant Porcine Adiponectin, C1Q And Collagen Domain Containing, FLAG-tagged
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Cat.#:ACRP30-3197HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human ACRP30
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Cat.#:ADIPOQ-1098HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADIPOQ, Fc tagged
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Cat.#:ADIPOQ-133HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human ADIPOQ protein, His-tagged
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Cat.#:ADIPOQ-14HTag:His|S
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOQ Protein, His/S-tagged
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Cat.#:ADIPOQ-19HTag:Flag
Source (Host):HEK293Species:Human
Product nameRecombinant Human ACRP30 headless, FLAG-tagged
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Cat.#:ADIPOQ-251HTag:DDK
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human ADIPOQ protein, DDK-tagged
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Cat.#:ADIPOQ-252HTag:DDK
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human ADIPOQ protein, DDK-tagged
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Cat.#:ADIPOQ-253HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADIPOQ protein, His-tagged
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Cat.#:ADIPOQ-254HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human ADIPOQ protein, His-tagged
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Cat.#:ADIPOQ-255HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOQ protein
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Cat.#:ADIPOQ-256HTag:DDK
Source (Host):CHOSpecies:Human
Product nameRecombinant Human ADIPOQ protein, DDK-tagged
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Cat.#:ADIPOQ-3647HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOQ, His-tagged
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Cat.#:ADIPOQ-391HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOQ Protein
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Cat.#:ADIPOQ-392HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ADIPOQ Protein, GST-tagged
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Cat.#:ADIPOQ-490HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Adiponectin, C1Q And Collagen Domain Containing
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Cat.#:ADIPOQ-4956HTag:N/A
Source (Host):High-5 insect cellsSpecies:Human
Product nameRecombinant Human Adiponectin, C1Q And Collagen Domain Containing
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Cat.#:ADIPOQ-4957HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Adiponectin, C1Q And Collagen Domain Containing
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Cat.#:ADIPOQ-7300HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADIPOQ protein, His-tagged
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Cat.#:ADIPOQ-7301HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADIPOQ, Fc-tagged
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Cat.#:ADIPOQ-856HTag:Flag
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADIPOQ protein, Flag-tagged
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Cat.#:Adipoq-13MTag:His|S
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Adiponectin Protein, His/S-tagged
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Cat.#:Adipoq-204MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Adipoq, His tagged
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Cat.#:Adipoq-32MTag:Flag
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Adipoq protein, Flag-tagged
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Cat.#:Adipoq-33MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Adipoq protein, His-tagged
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Cat.#:Adipoq-46MTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Adipoq
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Cat.#:Adipoq-500MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Adipoq Protein
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Cat.#:Adipoq-501MTag:His
Source (Host):Insect CellSpecies:Mouse
Product nameRecombinant Mouse Adipoq Protein, His-tagged
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Cat.#:Adipoq-5600MTag:His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Adiponectin, C1Q And Collagen Domain Containing, His-tagged
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Cat.#:Adipoq-75MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Adiponectin, Globular Domain
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Cat.#:Adipoq-79MTag:Flag
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Adipoq, FLAG-tagged
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Cat.#:Adipoq-194RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Adipoq protein, His-tagged
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Cat.#:Adipoq-502RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Adipoq Protein
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Cat.#:ADIPOQ-247RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ADIPOQ Protein, His-tagged
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Cat.#:ADIPOQ-2646DTag:His|GST
Source (Host):E. coliSpecies:Dog
Product nameRecombinant Dog ADIPOQ protein, His & GST-tagged
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Cat.#:ADIPOQ-2647CTag:His|T7
Source (Host):E. coliSpecies:Chicken
Product nameRecombinant Chicken ADIPOQ protein, His & T7-tagged
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Cat.#:ADIPOQ-7114CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ADIPOQ
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Cat.#:ADIPOQ-2645CTag:His
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle ADIPOQ protein, His-tagged
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Cat.#:ADIPOQ-2648PTag:His|GST
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig ADIPOQ protein, His & GST-tagged
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Cat.#:ADIPOQ-693HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOQ, 145aa
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Cat.#:ADIPOQ-199HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human ADIPOQ, His-tagged
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Cat.#:ADIPOQ-42HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADIPOQ, Globular Domain, His-tagged
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Cat.#:Adipoq-195RTag:Flag
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Adipoq, FLAG-tagged
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Cat.#:ADIPOQ-215HTag:N/A
Source (Host):Human pooled serumSpecies:Human
Product nameNative Human Adiponectin
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Cat.#:ADIPOQ-1526HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADIPOQ cell lysate
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Cat.#:ADIPOQ-2209MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse ADIPOQ cell lysate
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Involved Pathway

ADIPOQ involved in several pathways and played different roles in them. We selected most pathways ADIPOQ participated on our site, such as PPAR signaling pathway, AMPK signaling pathway, Adipocytokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADIPOQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
PPAR signaling pathway
SLC27A4; PPARD; FABP4; SCD5; APOA1A; ACSBG2; CYP8B1; SCDB; ANGPTL4; RXRA
AMPK signaling pathway
INSR; MTOR; ULK1; AKT1S1; PIK3CD; PPP2R5B; FASN; ADRa1A; PCK1; CAMKK2
Adipocytokine signaling pathway
PRKAB2; ACSL1B; AKT3A; PPARAB; PCK2; SLC2A1A; PRKAG3; AKT2L; MAPK10; MAPK8B
Type II diabetes mellitus
TNF; PKM2; SOCS1; SOCS3; PIK3R1; SOCS4; PIK3R3; PIK3CA; SLC2A2; IRS4
Non-alcoholic fatty liver disease (NAFLD)
PRKAA2; UQCRB; CEBPA; NDUFA6; NDUFA3; FASLG; SDHD; IKBKB; NDUFB11; PIK3R3

Protein Function

ADIPOQ has several biochemical functions, for example, cytokine activity, hormone activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADIPOQ itself. We selected most functions ADIPOQ had, and list some proteins which have the same functions with ADIPOQ. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein INHA; CMTM6; Cxcl15; IL17A/F3; IL29; Ifna11; CCL38A.5; IL17A/F2; TNFSF12; IL24
Function hormone activity
Related Protein INSL5A; GAST; INS; LRSAM1; PRL8A9; EPO; PRL3B1; STC1L; VIP; C1QTNF9
Function identical protein binding
Related Protein APOH; NISCH; COL7A1; RGMB; PSMA7; DAAM1; ERBB2; CD28; PARK2; TRAF6
Function protein binding
Related Protein ATP6V1G1; TFG; MKI67IP; PSRC1; FAM46C; TMEM173; RRAD; NAA10; WSB1; BMP7
Function protein homodimerization activity
Related Protein ADRB3; SLIT2; PON1; HNF1A; PKD2; TAP1; IL6ST; RBM11; HNF4A; PDCD6IP
Function receptor binding
Related Protein ACOX3; HAO1; ICOSLG; PVRL3; C3; CHRNA10; GFRA3; F2RL1; HFE; WNT11R
Function sialic acid binding
Related Protein ADIPOQ; L1CAM; FCN1; ST8SIA3; AGRN; SELE; SELP; Siglece; ST8SIA2

Interacting Protein

ADIPOQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADIPOQ here. Most of them are supplied by our site. Hope this information will be useful for your research of ADIPOQ.
C1QTNF9B; C1QTNF9

ADIPOQ Related Articles

Cai, X; Gan, Y; et al. The adiponectin gene single-nucleotide polymorphism rs1501299 is associated with hepatocellular carcinoma risk. CLINICAL & TRANSLATIONAL ONCOLOGY 16:166-172(2014).
Pang, YF; Dong, J; et al. Characterization, Neurosteroid Binding and Brain Distribution of Human Membrane Progesterone Receptors delta and epsilon (mPR delta and mPR epsilon) and mPR delta Involvement in Neurosteroid Inhibition of Apoptosis. ENDOCRINOLOGY 154:283-295(2013).