IL23R Protein, interleukin 23 receptor

IL23R

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IL23R

Official Full Name interleukin 23 receptor
Background The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2),
Synonyms IL23R; interleukin 23 receptor; interleukin-23 receptor; IL 23R; IL-23 receptor
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NS0
    • Tag :
    • Fc
    • His
    • GST
    • human
    • IgG1
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse IL23R-348M Recombinant Mouse IL23R protein, Fc-tagged HEK293 human/IgG1/Fc
    Human IL23R-589H Recombinant Human IL23R protein, His-tagged HEK293 His
    Human IL23R-1213HCL Recombinant Human IL23R cell lysate Human Cell N/A
    Human IL23R-8614H Recombinant Human IL23R protein, Fc-tagged HEK293 human/IgG1/Fc
    Human Il23R-8615H Recombinant Human Il23R, MIgG2a Fc-tagged CHO Fc
    Human Il23r-8617H Recombinant Human Il23r, HIgG1 Fc-tagged CHO Fc
    Mouse Il23r-5657M Recombinant Mouse Interleukin 23 Receptor, Fc-tagged NS0 Fc
    Mouse Il23r-5658M Recombinant Mouse Il23r, His-tagged Human Cell His
    Rat IL23R-1110R Recombinant Rat IL23R Protein, His-tagged HEK293 His
    Rat IL23R-1234RCL Recombinant Rat IL23R cell lysate Human Cell N/A
    Rat Il23r-1319R Recombinant Rat Il23r protein, His & GST-tagged E.coli His/GST
    Rat Il23r-8801R Recombinant Rat Il23r, Fc tagged Human Cell Fc
    Cynomolgus Monkey IL23R-1429CCL Recombinant Cynomolgus IL23R cell lysate Human Cell N/A
    Cynomolgus Monkey IL23R-8493C Recombinant Cynomolgus IL23R, Fc tagged Human Cell Fc
    Zebrafish IL23R-6305Z Recombinant Zebrafish IL23R Mammalian Cell His

    IL23R involved in several pathways and played different roles in them. We selected most pathways IL23R participated on our site, such as Cytokine-cytokine receptor interaction, IL23-mediated signaling events, Inflammatory bowel disease (IBD), which may be useful for your reference. Also, other proteins which involved in the same pathway with IL23R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IFNK; TGFB1A; CCL4L2; CXCR3; BMP7B; IL20RA; CCL27B; IL20RB; FLT3; IL-15RA
    IL23-mediated signaling events IL17F; IL23R; IL24
    Inflammatory bowel disease (IBD) IL1B; FOXP3; HLA-DRB3; TLR5; HLA-DRB4; NFKB1; HLA-DOA; HLA-DQA1; IL21; IFNG
    Jak-STAT signaling pathway STAT5B; IL5; STAT1B; PIM1; STAM2; STAT1A; CSF3R; PRL2; M17; IL13

    IL23R has several biochemical functions, for example, contributes_to interleukin-12 receptor binding, contributes_to interleukin-23 binding, contributes_to interleukin-23 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL23R itself. We selected most functions IL23R had, and list some proteins which have the same functions with IL23R. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to interleukin-12 receptor binding IL23R; IL12RB1; IL12B
    contributes_to interleukin-23 binding IL12RB1; IL23R
    contributes_to interleukin-23 receptor activity IL12RB1; IL23R
    protein binding HAT1; AZIN1; KHDC1B; ZNF302; ACCS; OSTB; FGF10; STAM; ASF1B; GLTP

    IL23R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL23R here. Most of them are supplied by our site. Hope this information will be useful for your research of IL23R.

    C1D

    Ciccacci, C; Perricone, C; et al. A Multilocus Genetic Study in a Cohort of Italian SLE Patients Confirms the Association with STAT4 Gene and Describes a New Association with HCP5 Gene. PLOS ONE 9:-(2014).
    Tillack, C; Ehmann, LM; et al. Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-gamma-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment. GUT 63:567-577(2014).

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