Recombinant Human IL23R protein, His-tagged

Cat.No. : IL23R-3082H
Product Overview : Recombinant Human IL23R protein(31-130 aa), fused to His tag, was expressed in E. coli.
Unit
Price
Qty
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Human
Tag : His
Form : The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole.
Protein length : 31-130 aa
AA Sequence : MSGHIWVEPATIFKMGMNISIYCQA AIKNCQPRKLHFYKNGIKERFQITR INKTTARLWYKNFLEPHASMYCTAE CPKHFQETLICGKDISSGYPPDIPD E
Purity : 95%, by SDS-PAGE with Coomassie Brilliant Blue staining.
Storage : Short-term storage: Store at 2-8°C for (1-2 weeks).
Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Reconstitution : Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.
Gene Name : IL23R interleukin 23 receptor [ Homo sapiens ]
Official Symbol : IL23R
Synonyms : IL23R; interleukin 23 receptor; interleukin-23 receptor; IL 23R; IL-23 receptor;
Gene ID : 149233
mRNA Refseq : NM_144701
Protein Refseq : NP_653302
MIM : 607562
UniProt ID : Q5VWK5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (10)

Ask a question
How does IL23R activation affect T-cell differentiation? 12/22/2022

IL23R activation promotes Th17 cell differentiation.

Does IL23R have alternative splicing variants? 02/20/2022

IL23R has multiple alternative splicing variants.

Does IL23R have any post-translational modifications that affect its stability? 08/23/2021

IL23R undergoes phosphorylation that affects its stability.

What is the half-life of IL23R protein in activated T-cells? 08/21/2020

The half-life of IL23R protein in activated T-cells is approximately 48 hours.

Are there any microRNAs that regulate IL23R expression? 06/16/2020

MicroRNAs like miR-20a regulate IL23R expression.

How does IL23R contribute to cytokine release? 02/15/2019

IL23R contributes to the release of pro-inflammatory cytokines like IL-17.

What role does IL23R play in autoimmune diseases? 08/22/2018

IL23R is implicated in autoimmune diseases like Crohn's.

How does IL23R expression change during infection? 10/12/2017

IL23R expression is upregulated during bacterial infection.

Does IL23R form homodimers or heterodimers? 08/15/2016

IL23R forms heterodimers with IL-12Rβ1.

What intracellular pathways are activated by IL23R? 08/06/2016

IL23R activates the JAK-STAT and NF-κB pathways.

Customer Reviews (3)

Write a review
Reviews
10/21/2020

    High specificity in ELISA. -

    04/28/2016

      Effective in autoimmune models. -

      03/30/2016

        Suitable for receptor binding studies. -

        Ask a Question for All IL23R Products

        Required fields are marked with *

        My Review for All IL23R Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        Stay Updated on the
        Latest Bioscience Trends

        Copyright © 2023 Creative BioMart. All Rights Reserved.

        Terms and Conditions        Privacy Policy