| Species : |
Bovine |
| Source : |
Yeast |
| Tag : |
Non |
| Description : |
Chemokine (C-X-C motif) ligand 11 (CXCL11) is a small cytokine belonging to the CXC chemokine family that is also called Interferon-inducible T-cell alpha chemoattractant (I-TAC) and Interferon-gamma-inducible protein 9 (IP-9). It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. |
| Sequences Of Amino Acids : |
FPMFKGGRCL CIGPGVKAVK VADIEKVSII YPTNNCDKTE VIITLKTHKG QRCLNPKAKQ AKAIIKKVQR KNSEKYKNI. |
| Formulation/Reconstitution : |
Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
| Purity : |
>95% as visualized by SDS-PAGE analysis. |
| Purification : |
Ion-exchange chromatography. |
| Biological Activity : |
The biological activity of recombinant bovine CXCL11 was determined in a chemotaxis assay using a Boyden chamber with bovine PBMC following initial culture with IL-2. Bioactivity is typically detected at 25 ng/mL. |
| Storage : |
Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles. |
| Pathways : |
Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Toll-like receptor signaling pathway |