Recombinant Human Cathepsin L2, His-tagged
Cat.No. : | CTSL2-681H |
Product Overview : | Recombinant human procathepsin V produced ininsect cellsis fused to a His-tag. 37kDa (SDS-PAGE). |
- Specification
- Gene Information
- Related Products
Cat. No. : | CTSL2-681H |
Description : | Recombinant glycosylated procathepsin V cloned from human cDNA and purified as full-length proenzyme. Can be activated in one step. Cathepsin V, a member of the papain family of cysteine proteases, has 78% identity to cathepsin L, but unlike cathepsin L is not widely expressed, being localized to thymus, testis, corneal epithelium, and macrophages. It is a strong elastase, also cleaving proteins such as the invariant chain (Ii), plasminogen, and kininogen. It is implicated in disease states such as cancer, angiogenesis, atherosclerosis, and myasthenia gravis. |
Source/Host : | insect cells. |
Application : | Study enzyme kinetics, cleave target substrates and screen for inhibitors. |
Concentration : | 0.5mg/ml. |
Purity : | ≥90%. |
Specific Activity : | 436 U/μg protein. One unit will hydrolyze one pmole Z-Leu-Arg-AMC substrate (Prod. No. BML-P229, 25 μM) per minute at 25°C, in 25mM NaOAc pH 5.5, 100mM NaCl, 1.0mM DTT. |
Formulation : | Liquid. In 25mM TRIS-HCl, pH 8.0, containing 100mM sodium chloride, 0.05% Tween-20 and 10% glycerol. |
Long Term Storage : | -80°C. |
Use/Stability : | Avoid extended periods unfrozen. This enzyme is stable for 6 months when stored as received under the above conditions. |
Handling : | After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles. |
Gene Name : | CTSL2 cathepsin L2 [ Homo sapiens ] |
Synonyms : | CTSL2; cathepsin L2; CTSU; CTSV; CATL2; MGC125957; EC3.4.22.43; Cathepsin L2; Cathepsin V; Cathepsin U; UNQ268/PRO305 |
Gene ID : | 1515 |
mRNA Refseq : | NM_001333 |
Protein Refseq : | NP_001324 |
MIM : | 603308 |
UniProt ID : | O60911 |
Chromosome Location : | 9q22.2 |
Pathway : | Lysosome |
Function : | cysteine-type endopeptidase activity; peptidase activity; protein binding |
Products Types
◆ Recombinant Protein | ||
CTSL2-2755H | Recombinant Human CTSL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSL2-614H | Recombinant Human CTSL2, His tagged | +Inquiry |
CTSL2-507H | Recombinant Human Cathepsin L2, His-tagged | +Inquiry |
CTSL2-4041C | Recombinant Chicken CTSL2 | +Inquiry |
CTSL2-751H | Recombinant Human Cathepsin L2, His-tagged | +Inquiry |
◆ Lysates | ||
CTSL2-7191HCL | Recombinant Human CTSL2 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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