Recombinant Human Mesoderm Development Candidate 2, His-tagged

• Cat.No.: MESDC2-3195H
• Product Overview: Recombinant Human MESDC2 (Met 1-Lys 230), fused with a His-tag at C-terminus, was expressed inHuman Cells.

Specification

• Species: Human
• Source: Human Cells
• Tag: His
• Protein Length: 1-230 a.a.
• Description: LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61 and MESDC2, is a member of the MESD family. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity resides in the N- and C-terminal unstructured regions. MESDC2 acts as a modulator of the Wnt pathway, since some LDLRs are coreceptors for the canonical Wnt pathway. MESDC2 is essential for specification of embryonic polarity and mesoderm induction.
• Purity: > 97% as determined by SDS-PAGE.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Predicted N Terminal: Ala 34.
• Formulation: Lyophilized from sterile PBS, pH 7.4.
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃.
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Molecular Mass: The recombinant human MESDC2 consists of 208 amino acids and has a predicted molecular mass of 23.6 kDa. The apparent molecular mass of rh MESDC2 is approximately 27 kDa in SDS-PAGE under reducing conditions.

Gene Information

• Gene Name: MESDC2 mesoderm development candidate 2 [ Homo sapiens ]
• Synonyms: mesoderm development candidate 2; LDLR chaperone MESD; mesoderm development protein; renal carcinoma antigen NY-REN-61; BOCA; MESD; KIAA0081; MESDC2; Renal carcinoma antigen NY-REN-61; Mesoderm development protein
• Gene ID: 23184
• mRNA Refseq: NM_015154
• Protein Refseq: NP_055969
• MIM: 607783
• UniProt ID: Q14696
• Chromosome Location: 15q13
• Function: molecular_function