"MESDC2" Related Products

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Recombinant Human Mesoderm Development Candidate 2, His-tagged

Cat. No.: MESDC2-3195H
Product Overview: Recombinant Human MESDC2 (Met 1-Lys 230), fused with a His-tag at C-terminus, was expressed inHuman Cells.
Description: LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61 and MESDC2, is a member of the MESD family. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity resides in the N- and C-terminal unstructured regions. MESDC2 acts as a modulator of the Wnt pathway, since some LDLRs are coreceptors for the canonical Wnt pathway. MESDC2 is essential for specification of embryonic polarity and mesoderm induction.
Source: Human Cells.
Purity: > 97% as determined by SDS-PAGE.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Predicted N Terminal: Ala 34.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Stability: Samples are stable for up to twelve months from date of receipt at -70℃.
Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Molecular Mass: The recombinant human MESDC2 consists of 208 amino acids and has a predicted molecular mass of 23.6 kDa. The apparent molecular mass of rh MESDC2 is approximately 27 kDa in SDS-PAGE under reducing conditions.
Gene Name: MESDC2 mesoderm development candidate 2 [ Homo sapiens ]
Synonyms: mesoderm development candidate 2; LDLR chaperone MESD; mesoderm development protein; renal carcinoma antigen NY-REN-61; BOCA; MESD; KIAA0081; MESDC2; Renal carcinoma antigen NY-REN-61; Mesoderm development protein
Gene ID: 23184
mRNA Refseq: NM_015154
Protein Refseq: NP_055969
MIM: 607783
UniProt ID: Q14696
Chromosome Location: 15q13
Function: molecular_function

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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