epcam
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  • Official Full Name
  • epithelial cell adhesion molecule
  • Background
  • This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
  • Synonyms
  • EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; antigen identified by monoclonal antibody AUA1; tumor-associated calcium signal transducer 1; 17-1A; 323/A3; CD326; CO-17A; EGP34; EGP40; GA733-2; HEA125; Ly74; MH99; MOC31; TACST-1; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; KS 1/4 antigen; Major gastrointestinal tumor-associated protein GA733-2; TACSTD1; human epithelial glycoprotein-2; Ep-CAM; membrane component, chromosome 4, surface marker (35kD glycoprotein); EGP; M1S2; CD326 antigen; Hegp314; ACSTD1; Adecatumumab; 503605-66-1; Citatuzumab bogatox; 945228-49-9; Citatuzumab bogatox; 945228-49-9; Tucotuzumab celmoleukin; 339986-90-2; Solitomab; 503605-66-1
Cat.#:EPCAM-7818HTag:Fc-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPCAM Protein, Fc-Avi-tagged, Biotinylated
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Cat.#:EPCAM-186CATag:Fc
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus EPCAM protein, Fc-tagged, APC labeled
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Cat.#:EPCAM-186CPTag:Fc
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus EPCAM protein, Fc-tagged, R-PE labeled
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Cat.#:Epcam-191MATag:Fc
Source (Host):NS0 CellsSpecies:Mouse
Product nameRecombinant Mouse Epcam protein, Fc-tagged, APC labeled
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Cat.#:Epcam-191MPTag:Fc
Source (Host):NS0 CellsSpecies:Mouse
Product nameRecombinant Mouse Epcam protein, Fc-tagged, R-PE labeled
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Cat.#:EPCAM-349HTag:Strep
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPCAM Protein, Strep-tagged
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Cat.#:EPCAM-350HTag:His & Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPCAM Protein, His & Avi-tagged, Biotinylated
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Cat.#:EPCAM-418HTag:HIgG1 Fc
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human EPCAM Protein (Met1-Lys265), HIgG1 Fc-tagged, Biotinylated
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Cat.#:EPCAM-475HATag:Fc
Source (Host):NS0 CellsSpecies:Human
Product nameRecombinant Human EPCAM protein, Fc-tagged, APC labeled
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Cat.#:EPCAM-475HPTag:Fc
Source (Host):NS0 CellsSpecies:Human
Product nameRecombinant Human EPCAM protein, Fc-tagged, R-PE labeled
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Cat.#:EPCAM-572HTag:Fc-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPCAM Protein, Fc-Avi-tagged, Biotinylated
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Cat.#:Epcam-7481RATag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Epcam protein, Fc-tagged, APC labeled
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Cat.#:Epcam-7481RPTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Epcam protein, Fc-tagged, R-PE labeled
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Cat.#:EPCAM-81HATag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPCAM protein, Fc-tagged, APC labeled
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Cat.#:EPCAM-81HPTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPCAM protein, Fc-tagged, R-PE labeled
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Cat.#:EPCAM-3367HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EPCAM Protein
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Cat.#:EPCAM-3368HTag:His/Flag/StrepII
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human EPCAM Protein, His/Flag/StrepII-tagged
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Cat.#:EPCAM-3370HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EPCAM Protein, GST-tagged
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Cat.#:EPCAM-195HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPCAM, His tagged
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Cat.#:EPCAM-257HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPCAM protein, His-tagged
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Cat.#:EPCAM-276HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPCAM, His-tagged, Biotinylated
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Cat.#:EPCAM-289HTag:DDK
Source (Host):Sf9 cellsSpecies:Human
Product nameRecombinant Human EPCAM Protein, DDK-tagged
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Cat.#:EPCAM-475HTag:Fc
Source (Host):NS0Species:Human
Product nameRecombinant Human EPCAM protein, Fc-tagged
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Cat.#:EPCAM-571HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human EPCAM, Fc-tagged, Biotinylated
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Cat.#:EPCAM-7063HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EPCAM, His-tagged
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Cat.#:EPCAM-72HTag:His
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human EPCAM protein, His-tagged
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Cat.#:EPCAM-77HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EPCAM protein
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Cat.#:EPCAM-7817HTag:Avi & His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPCAM protein, Avi & His-tagged
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Cat.#:EPCAM-81HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPCAM, Fc tagged
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Cat.#:Epcam-191MTag:Fc
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Epcam protein, Fc-tagged
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Cat.#:Epcam-283MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Epcam, His tagged
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Cat.#:EPCAM-2118RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat EPCAM Protein
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Cat.#:Epcam-7481RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Epcam, Fc tagged
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Cat.#:Epcam-7482RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Epcam, His tagged
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Cat.#:EPCAM-185CTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus EPCAM
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Cat.#:EPCAM-186CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus EPCAM, Fc-tagged
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Cat.#:EPCAM-202CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus EPCAM, His-tagged
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Cat.#:EPCAM-1482RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey EPCAM Protein, His-tagged
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Cat.#:EPCAM-1936CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken EPCAM
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Cat.#:EPCAM-6765CTag:His
Source (Host):E. coliSpecies:Chicken
Product nameRecombinant Chicken EPCAM protein, His-tagged
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Cat.#:EPCAM-2369ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish EPCAM
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Cat.#:EPCAM-6766PTag:His/T7
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig EPCAM protein, His & T7-tagged
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Cat.#:EPCAM-2525HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPCAM cell lysate
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Cat.#:EPCAM-2143MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse EPCAM cell lysate
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Cat.#:EPCAM-1434RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat EPCAM cell lysate
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Cat.#:EPCAM-001CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus EPCAM cell lysate
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Protein Function

EPCAM has several biochemical functions, for example, cadherin binding involved in cell-cell adhesion, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPCAM itself. We selected most functions EPCAM had, and list some proteins which have the same functions with EPCAM. You can find most of the proteins on our site.
Function
Related Protein
Function cadherin binding involved in cell-cell adhesion
Related Protein EPCAM
Function protein binding
Related Protein CTAG1A; CNOT7; SLC52A2; SORBS3; ELN; PLP2; STK40; C9orf86; CASK; MED11
Function protein complex binding
Related Protein BCAP31; CDKN1A; NCOA1; KRAS; LZTFL1; EP300; ATG101; ANKRD32; TULP3; NOG

Interacting Protein

EPCAM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPCAM here. Most of them are supplied by our site. Hope this information will be useful for your research of EPCAM.
CFTR

EPCAM Related Articles

Hyun, KA; Lee, TY; et al. Two-stage microfluidic chip for selective isolation of circulating tumor cells (CTCs). BIOSENSORS & BIOELECTRONICS 67:86-92(2015).
Gu, YJ; Ju, C; et al. Detection of circulating tumor cells in prostate cancer based on carboxylated graphene oxide modified light addressable potentiometric sensor. BIOSENSORS & BIOELECTRONICS 66:24-31(2015).